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BACKGROUND AND PURPOSE Proximal aortic plaques, especially in the aortic arch, have already been established as an important cause of stroke and peripheral embolism. However, aortic plaques situated in the descending thoracic aorta have recently been postulated as a potential embolic source in patients with cryptogenic cerebral infarction through retrograde aortic flow. The aim of the present s...
Rotaviruses (RV) are a major cause of severe gastroenteritis (GE) in children aged<5 y. For the first time in China, we assessed the efficacy of two oral doses of the human rotavirus vaccine (RIX4414) in infants during the first two years of life (113808/NCT01171963). Healthy infants aged 6-16 weeks were randomized (1:1) to receive two oral doses of either the RIX4414 vaccine/placebo according ...
زمینه و هدف: فلوئور به مقدار ناچیزی در جیره غذایی افراد وجود دارد و عمدهترین راه جذب آن از طریق آب آشامیدنی است. استاندارد 1053 مؤسسه استاندارد و تحقیقات صنعتی ایران، میزان فلوئور در آب را بسته به میزان دما، بین 6/0 تا mg/l 1/7 توصیه میکند. مطالعه حاضر با هدف تعیین میزان فلوئور در منابع آب آشامیدنی استان خراسان جنوبی انجام شد. روش تحقیق: در این مطالعه توصیفی- تحلیلی، طیّ یک سال، به روش سرشما...
the new line (kauz/pastor//bav92/rayon cmss00m02400s-030m-030wgy-030m-9m-0y) (gaboos cultivar) was evaluated at gachsaran and gonbad agricultural research stations in the first time in 2006-2007. due to optimum earliness, plant height, kernel weight and successful performance of grain yield in observation nursery, preliminary and advanced yield trials (2007-2009), this genotype along to 16 prom...
فلور واژن یک اکوسیستم سیار هست که به آسانی تغییر می کندف هرچند که چهار عامل ترشحات واژن تا 95 درصد مسبب التهاب واژن هستند. واژینیت کاندیدیایی ناشی از التهاب دیواره وازن به وسیله قارچ کاندیدیا البیکانس است. مطالعه حاضر برای برای تعیین فراوانی شیوع واژینیت کاندیدیایی در زنان مراجعه کننده به مراکز بهداشتی یزد و نقش ایمنی سلولی در واژینیت کاندیدیایی انجام شد. مطالعه ای توصیفی- تحلیلی و مقطعی که از ...
A series of N-hydroxyformamide tumor necrosis factorconverting enzyme (TACE)/matrix metalloprotease (MMP) inhibitors were evaluated for their potential to induce human cytochrome P450 3A (CYP3A). Two in vitro assays were used: 1) a cell-based reporter gene assay for activation of the pregnane X receptor (PXR), and 2) a primary “sandwich” culture of human hepatocytes. Approximately 50 TACE/MMP i...
This commentary is on the original article by Knuutinen et al. pages 1066–1074 of this issue. Leukodystrophies and leukoencephalopathies, a heterogeneous set conditions now often referred to as ‘genetic white matter disorders’ (GWMDs), have been problematic for diagnosis treatment. Three major phases marked studies into GWMDs. First, with advent widespread use magnetic resonance imaging (MRI) i...
Abstract Study question To explore the effect of high concentration E2 after controlled ovarian hyperstimulation (COH) on extracellular matrix cervical tissue in second trimester. Summary answer The COH promotes ECM degradation leading to insufficiency pregnancy ART by up-regulating UBA52. What is known already Assisted reproductive technology (ART) a double-edged sword. While effectively solvi...
Towards a New Model of Abstraction in the Engineering of Software Gregor Kiczales Xerox Palo Alto Research Center We now come to the decisive step of mathematical abstraction: we forget about what the symbols stand for: : : [The mathematician] need not be idle; there are many operations he can carry out with these symbols, without ever having to look at the things they stand for. Hermann Weyl, ...
Mechanosensitive ion channels have been described in many types of cells. These channels are believed to transduce pressure signals into intracellular biochemical and physiological events. In this study, the patch-clamp technique was used to idendfy and characterize a mechanosensitive ion channel in rat atrial cells. In cell-attached patches, negative pressure in the pipette activated an ion ch...
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