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تعداد نتایج: 1858738 فیلتر نتایج به سال:
OBJECTIVE Hyaluronan (HA) plays a role in keratinocyte proliferation and differentiation. In addition, HA has been shown to have different biological activities depending on its molecular weight. It has been reported that HA-mediated CD44 activation regulates keratinocyte differentiation. Therefore, the aim of this study was to investigate the influence of HA tetrasaccharides (HA4) on the regul...
To investigate the effects of chemical, organic and biological fertilizers application on the quantitative and qualitative characteristics of seedless barberry (Berberis vulgaris cv. Asperma) an experiment was conducted as split plot randomized complete block design with three replications in commercial garden in Qaen during 2016. Main-treatments comprised four application type of fertilizer (1...
In PC12 cells, Ha-Ras modulates multiple effector proteins that induce neuronal differentiation. To regulate these pathways Ha-Ras must be located at the plasma membrane, a process normally requiring attachment of farnesyl and palmitate lipids to the C terminus. Ext61L, a constitutively activated and palmitoylated Ha-Ras that lacks a farnesyl group, induced neurites with more actin cytoskeletal...
INTRODUCTION Microorganisms are essential in the development of periradicular diseases and are the major causative factors associated with endodontic treatment failures. Microbial biofilms are communities of bacteria that attach to surfaces and form heterogeneous three-dimensional structures. The purpose of this study was to develop a biofilm model that closely mimicked in vivo biofilm and to d...
Hyaluronate-hydroxyethyl acrylate blend gel (HA-PHEA) were prepared to modify the brittleness of hyaluronate gel (HA) and the characteristics of HA-PHEA gel were compared with those of HA and polyhydroxyethyl acrylate (PHEA) gels. These gels were high in water content and transparent. HA-PHEA gel was improved in viscoelastic properties due to the elasticity and the high affinity with water of P...
In this study, the effects of nitrogen fertilizer and plant growth regulator (ethephon) application on leaf chlorophyl, stem height and diameter, stalk yield, total sugar and bioethanol of sweet sorghum were determined. Four nitrogen treatments 0, 100, 200 and 300 Kg Urea ha-1 and four ethephon concentrations 0, 800, 1000, and 1200 ppm were applied on sweet sorghum in a split plot on randomized...
OBJECTIVE To conduct a phase I-II clinical trial of hyaluronan-cisplatin nanoconjugate (HA-Pt) in dogs with naturally occurring malignant tumors. ANIMALS 18 healthy rats, 9 healthy mice, and 16 dogs with cancer. PROCEDURES HA-Pt was prepared and tested by inductively coupled plasma mass spectrometry; DNA-platinum adduct formation and antiproliferation effects of cisplatin and HA-Pt were compare...
Macroporous single phase hydroxyapatite (HA) and biphasic HA/β-tricalcium phosphate with 33% post-sinter hydroxyapatite (HA/β-TCP) were combined with 25 or 125 μg recombinant human transforming growth factor-β3 (hTGF-β(3)) to engineer a super activated bioreactor implanted in orthotopic calvarial and heterotopic rectus abdominis muscle sites and harvested on day 30 and 90. Coral-derived calcium...
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