Background: Cassava, an important tropical crop, has remarkable drought tolerance, but is very sensitive to cold. The growth, development, and root productivity of cassava are all adversely affected under cold and drought. Methods: To profile the transcriptional response to cold and drought stresses, cassava seedlings were respectively subjected to 0, 6, 24, and 48 h of cold stress and 0, 4, 6,...

Of somatosensory modalities, cold is one of the more ambiguous percepts, evoking the pleasant sensation of cooling, the stinging bite of cold pain, and welcome relief from chronic pain. Moreover, unlike the precipitous thermal thresholds for heat activation of thermosensitive afferent neurons, thresholds for cold fibers are across a range of cool to cold temperatures that spans over 30 °C. Unti...

While the pure sensation of cold is evoked by activation of a specific set of afferent channels, an additional set is believed to be activated by noxious low-temperature stimuli evoking cold pain. At primary afferent level, the channels concerned with the cold fraction of cold pain are served by myelinated A delta cold-specific fibres, whereas those concerned with the pain fraction are served b...

Cold denaturation is a general property of globular proteins, but it is difficult to directly characterize because the transition temperature of protein cold denaturation, T(c), is often below the freezing point of water. As a result, studies of protein cold denaturation are often facilitated by addition of denaturants, using destabilizing pHs or extremes of pressure, or reverse micelle encapsu...

BACKGROUND Asthma is a serious global health problem. However, few studies have investigated the relationship between cold spells and pediatric outpatient visits for asthma. OBJECTIVE To examine the association between cold spells and pediatric outpatient visits for asthma in Shanghai, China. METHODS We collected daily data on pediatric outpatient visits for asthma, mean temperature, relati...

THE FUTURE OF MAN. Predictions of a Biologist. By P. B. Medawar. New York, Basic Books Inc., 1960, 128 pp. $3.00. This book proves that scientific distinction and the ability to write lucidly and entertainingly are not necessarily incompatible. Many fascinating points are raised, few definitive answers are given. Why do children born between May and October have slightly higher scores in intell...

Individuals often lose confidence in their prospects as they approach the ‘moment of truth.’ An axiomatic model of such individuals is provided. The model adapts and extends (by relaxing the Independence axiom) Gul and Pesendorfer’s model of temptation and self-control to capture an individual who changes her beliefs so as to become more pessimistic as payoff time approaches. In a variation of ...

The purpose of this study was to determine the role of the proinflammatory cytokine interleukin (IL) 6 in cold-induced hypertension. Four groups of male Sprague-Dawley rats were used (6 rats per group). After blood pressure was stabilized, 3 groups received intravenous delivery of adenoassociated virus carrying IL-6 small hairpin RNA (shRNA), adenoassociated virus carrying scrambled shRNA, and ...

BACKGROUND Acquired cold urticaria (ACU) is usually a self-limited, sporadic, cutaneous disease diagnosed based on history and a positive cold stimulation time test (CSTT) result. We describe 3 unrelated families (A, B, and C) with lifelong atypical cold urticaria distinguished from ACU and familial cold autoinflammatory syndrome. OBJECTIVE We sought to describe a new hereditary disease of co...

OBJECTIVE The Bashang Long-tail chicken (BS), an indigenous Chinese breed, is considered cold tolerant. We selected BS, the Rhode Island Red (RIR), and their reciprocal crossbreds for the present study. The objectives were: i) to validate whether BS is cold tolerant and whether egg production and cold tolerance of crossbreds could be improved; and ii) to determine the physiological characterist...