Subcutaneous (SC) injection is a common route of drug administration; however, site pain (ISP) might create negative patient experience. We evaluated ISP, bioequivalence, and overall safety new citrate-free (CF) formulation ixekizumab, high-affinity monoclonal antibody that selectively targets interleukin-17A. Two phase 1, single-blind studies were conducted in healthy participants. The crossov...

The YNi9In2-type copper-rich compounds RECu9Cd2 (RE = La, Ce, Pr, Nd) were synthesized directly from the elements in sealed niobium ampoules in an induction furnace and were characterized by powder X-ray diffraction. The structure of PrCu9Cd2 was refined from single-crystal Xray diffractometer data: P4/mbm, a = 849.0(3), c = 498.2(3) pm, wR2 = 0.0418, 374 F2 values, 23 variables. The structure ...

Krakowskie Studia z Historii Państwa i Prawa » Tom 14 (2021) Zeszyt 3 Evans, Richard J. The Hitler Conspiracies: Third Reich and the Paranoid Imagination. Allen Lane, 2020, 288 pp. A

The detonation initiation characteristics of a single tube liquid-fueled pulse combustor (PDC) is investigated at different inlet air temperatures in this paper. inner diameter the PDC 62 mm. Gasoline and are used as fuel oxidant, respectively. temperature 288–523 K operating frequency 10~30 Hz. experimental results show that deflagration to transition (DDT) distance, time, DDT time jet ignitio...