The biotech company Lorus has announced the enrollment of the first cancer patient in a Phase I clinical study evaluating its small molecule anticancer drug candidate LOR-253. The open-label, dose escalation study will enroll patients with advanced or metastatic solid tumors for which no effective therapy is currently available, or whose cancer has not responded to conventional or standard ther...

Robotica / Volume 29 / Issue 02 / March 2011, pp 245 253 DOI: 10.1017/S026357471000010X, Published online: 30 April 2010 Link to this article: http://journals.cambridge.org/abstract_S026357471000010X How to cite this article: Jingzhou (James) Yang, Tim Marler and Salam Rahmatalla (2011). Multi-objective optimization-based method for kinematic posture prediction: development and validation. Robo...

The catalytic activity of trypsin-like serine proteases is in many cases regulated by conformational changes initiated by binding of physiological modulators to exosites located distantly from the active site. A trypsin-like serine protease of particular interest is urokinase-type plasminogen activator (uPA), which is involved in extracellular tissue remodeling processes. Herein, we used hydrog...

Introduction..................................................................... 232 Pertinent Properties of the Cell Envelope ......... ............................. 233 E. coli Fatty Acid Auxotrophs .............. ................................... 233 Specific inhibitors of Fatty Acid Synthesis ......... ............................ 234 LIPID BILAYER PHASE PROPERTIES ........ ................

In the near future, wireless networks will certainly run real-time applications with special Quality of Service (QoS) requirements. In this context micro mobility management schemes such as Fast Handovers over Hierarchical Mobile IPv6 (F-HMIPv6) will be a useful tool in reducing Mobile IPv6 (MIPv6) handover disruption and thereby to improve delay and losses. However, F-HMIPv6 alone does not sup...