This chapter is concerned with the prevalence of non-communicable chronic diseases (NCDs) such as obesity, hypertension, diabetes mellitus and coronary heart disease (CHD) due to nutrition transition and increasing urbanization in developing countries in general and in India in particular. It briefly describes the present position of rural-urban migration during 1991 to 2001 in India with speci...

I N T R O D U C T I O N Changes in ion permeability at one epithelial cell membrane are often associated with modifications in ion t ransport at the opposing membrane ("cross-talk") (Schultz, 1981; Diamond, 1982). The nature of the cellular signal for "cross-talk" is not known, however, in a companion paper (Harvey et al., 1988) we have shown that sodium and potassium conductances in frog skin ...

Insecticidal cry and vip genes from Bacillus thuringiensis (Bt) have been used for control of lepidopteran insects in transgenic crops. However, novel genes are required for gene pyramiding to delay evolution of resistance to the currently deployed genes. Two PCR-based techniques were employed for screening of cry2-type genes in 129 Bt isolates from diverse habitats in India and 27 known Bt str...

Infectious bronchitis (IB) is an acute, highly contagious, and economically important viral disease of chickens. The S1 subunit from Spike (S) protein plays the major role in protective immunity and is involved in the host-virus interactions, as well as infectious bronchitis virus (IBV) serotyping. Aim of the present study was multi-aspect analysis of the molecular and immunological features of...

PURPOSE The interleukin-23 receptor (IL-23R) has been shown to be associated with ankylosing spondylitis (AS) in many different populations. This study examined whether IL-23R polymorphisms were associated with susceptibility to this disease in a Chinese Han population. METHODS Three single-nucleotide polymorphisms (SNP), rs7517847, rs11209032, and rs17375018, were genotyped in 291 AS patient...

A genome's ability to produce two separate sexually dimorphic phenotypes is an intriguing biological mystery. Microarray-based studies of a handful of model systems suggest that much of the mystery can be explained by sex-biased gene expression evolved in response to sexually antagonistic selection. We present the first whole-genome study of sex-biased expression in the red flour beetle, Tribol...