نتایج جستجو برای: 218 ق
تعداد نتایج: 10424 فیلتر نتایج به سال:
The mei-218 gene product is required for both meiotic crossing over and for the production of recombination nodules, suggesting that these organelles are required for meiotic exchange. In this study the null phenotype of mei-218 was defined through the analysis of three preexisting and five new alleles. Consistent with previous studies, in homozygous mi-218 mutants meiotic crossing over is redu...
موضوع این پایان نامه بررسی 49 پرسش از متنی است به زبان پارسی میانه به نام (( روایات آذر فرنبغ فرخزادان)) این کتاب مشتمل بر 147 پرسش و پاسخ است که زردشتیان آن زمان از هیربد آذر فرنبغ پیشوای خود پرسیده اند. این اثر شامل پرسشهایی درباره ازدواج فرزندخواندگی، حضانت، ارث، طهارت و تجاست، گرویدن زردشتیان به اسلام و تبعات آن، زنا با کافر، گناه و ثواب، آیینهای دینی، بخشش، سوگند و توسل به آزمایش دینی، وام...
A variety of extracellular signals lead to the phosphorylation and activation of mitogen-activated protein kinases (MAP kinases). An activator of MAP kinases, Mek1, phosphorylates MAP kinases at threonine and tyrosine residues and is itself phosphorylated at serine-218 and -222 by the protooncogene product Raf-1. By introducing negatively charged residues that may mimic the effect of phosphoryl...
BACKGROUND Optimization of conditions during recombinant protein production for improved yield is a major goal for protein scientists. Typically this is achieved by changing single crucial factor settings one at a time while other factors are kept fixed through trial-and-error experimentation. This approach may introduce larger bias and fail to identify interactions between the factors resultin...
In three lymphoma cell lines carrying t(14;18), named FL-18, FL-218, and FL-318, the genomic organization of IgH gene was compared with the expression of bcl-2 gene; the t(14;18) of the FL-18 cells occurred downstream from the major breakpoint cluster region (mbr) of a bcl-2 gene, and that of the FL-218 and FL-318 cells within the mbr. The FL-318 expressed the normal-sized bcl-2 transcript of 8...
In cancer, glycolysis driving enzymes and their regulating microRNAs are one of the key focus of oncology research lately. The glycolytic enzyme hexokinase 2 (HK2) is crucial for the Warburg effect in human glioma, the most common malignant brain tumor. In the present study, we studied the tumorigenic role of HK2 in glioma, and clarified the mechanism of miR-218 induced HK2 regulation in glioma...
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