Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal tract. In the United States, it is the third most commonly diagnosed cancer, next only to breast and lung. It is the second most common cause of cancer-related death both in the USA and in the UK. (www. cancer. org, O’Connell et. al. 2004a, Leff et. al. 2007). Its incidence has risen rapidly in Asia to pose a problem ...

Nasal cavity is an important component of respiration system for the various physiological functions (Elad et al., 2008; Lee, 2010). Due to its complicated geometry, flow patterns are difficult to visualize inside 3D spaces. By adopting the ISOMAP algorithm (Tenenbaum et al., 2000) implemented in Matlab, the surface of a nasal cavity, together with characteristic lines serving as visual markers...

Cow’s milk allergy (CMA) is one of the most commonly reported food allergies in infancy (Prescott et al. 2013). Incidence of CMA peaks during early childhood and tends to recede later, with the reported prevalence to be 0.6–2.5% in pre-schoolers, 0.3% in older children and teens, and less than 0.5% in adults (Fiocchi et al. 2010). A recent study performed in Europe supports these findings by de...

INTRODUCTION A variety of craniofacial organs and tissues, such as the Meckel’s cartilage, maxillary and mandible bone, trigeminal ganglion and dentin-producing odontoblasts, derive from craniofacial neural crest cells (Chai et al., 2000; Chung et al., 2009). Despite originating from the same progenitor population, craniofacial bone and tooth exhibit distinct developmental, morphological and hi...

Renal tumors account for more than 50,000 new cases annually in the United States with a rising incidence (Chow et al., 1999). This is mainly because of an increase in diagnosis due to widespread use of cross-sectional imaging (Pantuck et al., 2001). Renal cell carcinoma constitutes 4% of all adult malignancies (American Cancer Society, 2008) and about 70 to 80 percent of patients presenting wi...

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide [Serag et al., 2007, Liovet et al., 2003, Yang et al., 2010]. More than 500,000 people are diagnosed with HCC every year, and it remains the leading cause of death among patients with hepatitis B virus (HBV), hepatitis C virus (HCV) and alcohol-induced liver cirrhosis. One of the main obstacles for treating HCC is l...

INTRODUCTION Behavioral differences between males and females often arise from sexually dimorphic neurons and circuits (Cooke et al., 1998; Wade and Arnold, 2004; Villella and Hall, 2008; Paus, 2010). Stereotyped male behaviors in Drosophila melanogaster provide the basis for our current understanding of the genetic mechanisms and neural substrates that generate sexually dimorphic behaviors (Ya...

The resurgence of motivation in social psychology has been a welcome addition to the cognitive revolution, though a theory-based approach to motivational content has remained conspicuously absent. Kenrick, Griskevicius, Neuberg, and Schaller (2010, this issue) dust off Maslow's hierarchy of needs and find this content in the form of evolutionarily inspired, fundamental motives. Their new framew...

article on adolescent drinking, van der Vorst and colleagues (2010) made recommendations for policy and parenting that are unsupported by their own data and are, I would argue, potentially harmful. The article was presented as a refutation of the idea that parents should model moderate/mealtime drinking for their adolescent offspring (as by permitting the adolescent a few sips of an alcoholic b...