Many studies have investigated misregulation of miRNAs relevant to multiple sclerosis (MS) pathogenesis. Abnormal miRNAs can be used both as candidate biomarker for MS diagnosis and understanding the disease miRNA-mRNA regulatory network. In this comprehensive study, misregulated miRNAs related to MS were collected from existing literature, databases and via in silico prediction. A multi-staged...

Efficient parallelization of genetic algorithms (GAs) on state-of-the-art multi-threading or many-threading platforms is a challenge due to the difficulty of schedulation of hardware resources regarding the concurrency of threads. In this paper, for resolving the problem, a novel method is proposed, which parallelizes the GA by designing three concurrent kernels, each of which running some depe...

This paper gives an overview of a proposed strategy for the “Cows and Herders” scenario given in the Multi-Agent Programming Contest 2009. The strategy is to be implemented using the Jason platform, based on the agent-oriented programming language AgentSpeak. The paper describes the agents, their goals and the strategies they should follow. The basis for the paper and for participating in the c...

Background: Today, several vaccines have been developed to prevent infectious diseases. The older first-generation vaccines may have many problems. In this regard, genetic engineering plays an important role using tools such as shuttle vectors to develop recombinant DNA vaccines that usually include plasmid constructed so that can propagate in two different host species. The present study revie...

Static risk analysis techniques (SRATs) use event graphs and assessment models. Those are not time-based hence inadequate to model dynamic stochastic systems. This paper proposes a novel approach such systems using Dynamic Fault Trees (DFT). The proposed is called Generic Agent-Based Model (GDABM) for analysis. GDABM built on top of the well-known Modeling Simulation (ABMS) technique. can syste...

The novel Malekan-e- Azab is the latest published work by Abu Torab-e Khosravi. The significance which is always assumed by Khosravi for words and writing is conspicuously seen in this novel as well; however, the author’s attempt to develop novel atmosphere and techniques has added a new dimension of complexity. To fully appreciate this complication and to gain an understanding of the dis...

This paper presents a new hybrid method for optimal multi-objective reconfiguration in a distribution feeder in addition to determining the optimal size and location of multiple-Distributed Generation (DG). The purposes of this research are mitigation of losses, improving the voltage profile and equalizing the feeder load balancing in distribution systems. To reduce the search space, the improv...