نتایج جستجو برای: 2 hdl
تعداد نتایج: 2542471 فیلتر نتایج به سال:
Aim: Dyslipidemia is an established risk factor for cardiovascular disease. Increased triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) levels, and decreased high (HDL-C) levels were associated with increased risk. Recently, comprehensive lipid profile indices derived from these conventional parameters have attracted to attention. Atherogenic index of plasma (AIP) one the calculate...
antioxidant, antithrombotic, and antiinflammatory properties of HDL particles (2). Interestingly, structural modifications of HDL mediated by various mechanisms, including glycation, oxidation, and enzymatic degradation, may affect their functional and atheroprotective properties (3). This may suggest that not only quantity but also quality of HDL particles play a role in the damage of endothel...
BACKGROUND HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore assessed HDL particles by NMR spectroscopy and conducted a large-scale candidate gene association analysis. METHODOLOGY/PRINCIPAL FIN...
OBJECTIVE This study investigates effects of short-term administration of high-density lipoproteins (HDL) and a statin on atherosclerosis in cholesterol-fed rabbits. Effects of HDL apolipoprotein and phospholipid composition have also been investigated. METHODS AND RESULTS Aortic atherosclerosis was established over 17 weeks in 46 rabbits by balloon denudation and cholesterol feeding. During ...
OBJECTIVE The investigation of the relationship between high density lipoprotein (HDL) and adiponectin. DESIGN Thirty-seven obese or overweight [body mass index ≥27 Kg/m(2)], hypertriglyceridemic patients underwent one of the following interventions for 3 months: 1) Low-calorie diet (n=19), 2) Low-calorie diet plus fenofibrate (n=18). RESULTS Circulating total adiponectin did not change sig...
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux.
Our objective was to evaluate the associations of individual apolipoprotein A-I (apoA-I)-containing HDL subpopulation levels with ABCA1- and scavenger receptor class B type I (SR-BI)-mediated cellular cholesterol efflux. HDL subpopulations were measured by nondenaturing two-dimensional gel electrophoresis from 105 male subjects selected with various levels of apoA-I in pre-beta-1, alpha-1, and ...
Background The combination of gamma-glutamyl transferase (GGT) and high-density lipoprotein cholesterol (HDL-C) (GGT/HDL-C) is a novel noninsulin-based marker for assessing the risk nonalcoholic fatty liver disease type 2 diabetes mellitus. However, whether GGT/HDL-C ratio related to incident cardiovascular (CVD) not well known. Therefore, we aimed investigate longitudinal effect on CVD in thre...
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