BACKGROUND Soluble fibers lower serum lipids, but are difficult to incorporate into products acceptable to consumers. We investigated the physiological effects of a concentrated oat beta-glucan on cardiovascular disease (CVD) endpoints in human subjects. We also compared the fermentability of concentrated oat beta-glucan with inulin and guar gum in a model intestinal fermentation system. METH...

Candida albicans is an opportunistic fungal pathogen that poses a serious threat to immunocompromised patients. Candida’s greatest mechanism of defense against the host immune system is its cell wall. It has been shown that chitin, a component of Candida’s cell wall, is synthesized during cellular stress. We investigated the temporal dynamics of chitin deposition during immune attack by perform...

Glucans are fungal cell wall polysaccharides which stimulate innate immune responses. We determined the minimum unit ligand that would bind to glucan receptors on human U937 cells using laminarin-derived pentaose, hexaose, and heptaose glucan polymers. When U937 membranes were pretreated with the oligosaccharides and passed over a glucan surface, only the heptasaccharide inhibited the interacti...

The article is devoted to the study of isolation processes, chemical structure and rheological properties chitin-glucan complexes from biomass Armillaria mellea. Because studies, it was found that yield ranged 11.0 24.9% with a degree deacetylation 24 55%. maximum obtained by treating fruiting bodies fungi at stage deproteinization 3% aqueous solution sodium hydroxide mechanical stirring 225 rp...

terol (Davidson et al., 1991; Klopfenstein and Hoseney, 1987). Oat (Avena sativa L.) -glucan lowers serum cholesterol in hu-Glucan is a cell wall polysaccharide found in seeds mans. Development of oat cultivars with greater groat (caryopsis) -glucan content would increase the nutritional and economic value of the Gramineae (Stinard and Nevins, 1980; Nevins et of the crop. The objectives of this...

We have previously found that a partially 2-deoxygenated (P2D)-amylose, produced by glucan phosphorylase (GP)-catalyzed enzymatic copolymerization, shows hydrophobic nature. Based on this finding, the present study demonstrates hydrophobization of strong hydrophilic polypeptide, i.e., poly(γ-glutamic acid) (PGA), grafting P2D-amylose chains via GP-catalyzed approach. After maltooligosaccharide ...

β-Glucan is a valuable functional ingredient and various extraction techniques are available for its extraction. Choice of an appropriate extraction technique is important as it may affect the quality, structure, rheological properties, molecular weight, and other functional properties of the extracted β-glucan. These properties lead to the use of β-glucan into various food systems and have imp...

Both moderate exercise and the soluble oat fiber beta-glucan can increase immune function and decrease risk of infection, but no information exists on their possible combined effects. This study tested the effects of moderate exercise and oat beta-glucan on respiratory infection, macrophage antiviral resistance, and natural killer (NK) cell cytotoxicity. Mice were assigned to four groups: exerc...

The complement system is important for host resistance to hematogenously disseminated candidiasis. However, modulation of complement activation by cell wall components of Candida albicans has not been characterized. Although intact yeast display mannan on the surface, glucan, typically located in the interior, becomes exposed during C. albicans infection. We show here the distinct effects of ma...

Mushroom β-glucan has the ability to affect many cellular functions, including cellular glucose uptake. Although cumulative evidence in literature suggests a connection between β-glucan and reduction of blood glucose concentration, a mechanism of how β-glucan affects cellular glucose uptake has not been demonstrated. In this study, we analyzed the effect of β-glucan containing polysaccharide ex...