AIMS/HYPOTHESIS To investigate secular trends in cardiovascular disease (CVD) risk factors during a decade of follow-up in a Middle Eastern cohort, and to compare observed trends between diabetic and non-diabetic populations. METHODS In a population of 6181 participants (2622 males and 3559 females), diabetes status and CVD risk factors were evaluated in 4 study phases from 1999-2011. 1045 su...

Background: Prediabetes is an important risk factor for developing type 2 diabetes and cardiovascular diseases. The current study aims to investigate the changes in miR-204 serum glucose following eight weeks of high-intensity interval training (HIIT) men with prediabetes. Materials Methods: In this quasi-experimental a pre-test/post-test design, 24 middle-aged (aged 40-50 years) prediabetes (F...

BACKGROUND Elevated concentrations of plasma glucose appear to play a role in memory impairment, and it has been suggested that insulin might also have a negative effect on cognitive function. Our aim was to study whether glucose, insulin or insulin resistance are associated with episodic or semantic memory in a non-diabetic and non-demented population. METHODS We linked and matched two popul...

his study was carried out to determine the importance of type 2 Diabetes mellitus as a risk factor for osteoporosis in postmenopausal women. Materials and Methods: This study was conducted in 2004 on 40 diabetic and 40 healthy postmenopausal women attending the endocrine clinics in Zanjan. These two groups were matched in terms of age, length of their menopausal period and body mass index. Seru...

background: asymptomatic bacteriuria (asb) is common among women with diabetes. the aim of this study was determine the prevalence of and risk factors for asb in women with diabetes type 2 in shahre-kord city of iran. methods: in a six months period (april- september 2005), a total of 100 women with diabetes (type 2) and 100 healthy women without diabetes as control group were investigated for ...

OBJECTIVE To evaluate the prevalence of diabetic nephropathy and microalbuminuria in pregnant women with type 2 diabetes in comparison with type 1 diabetes and to describe pregnancy outcomes in these women following the same antihypertensive protocol. RESEARCH DESIGN AND METHODS Among 220 women with type 2 diabetes and 445 women with type 1 diabetes giving birth from 2007-2012, 41 women had d...

OBJECTIVE Diabetes, the leading cause of end-stage renal disease in the U.S., is believed to involve activation of the renin angiotensin system (RAS) as a risk factor for nephropathy. RAS activation occurs in healthy women using oral contraceptives (OCs), but the effects of OC use on the diabetic kidney are unclear. RESEARCH DESIGN AND METHODS Renal plasma flow (RPF) response to captopril, as...

Diabetes mellitus (DM) and osteoporosis are common diseases and their prevalence increases with age. Several investigations have indicated that type 1 DM has a significant relationship with bone loss, whereas in type 2 diabetes, this relationship is controversial. Therefore, this study was conducted to determine the relationship between osteoporosis and type 2 DM in elderly people. This populat...

The purpose of this study was to understand the health benefits of line dancing activity in Korean middle-aged women. This study explored how Korean middle-aged women perceive health benefits through lived experiences of line dancing in their leisure time. Three themes emerged related to health benefits: (1) psychological benefit, (2) physical benefit, and (3) social benefit. This finding sugge...

IMPORTANCE Microglia have been associated with inflammatory changes underlying diabetic retinopathy. OBJECTIVE To investigate whether low-dose oral doxycycline monohydrate, a drug capable of inhibiting microglial activation, can improve or slow the deterioration of retinal function and whether it can induce regression or slow progression of diabetic retinopathy in patients with mild to modera...