CITATION Ranieri VM, Thompson BT, Barie PS, Dhainaut JF, Douglas IS, Finfer S, Gårdlund B, Marshall JC, Rhodes A, Artigas A, Payen D, Tenhunen J, Al-Khalidi HR, Thompson V, Janes J, Macias WL, Vangerow B, Williams MD: Drotrecogin alfa (activated) in adult patients with septic shock. N Engl J Med 2012, 366:2055-2064. BACKGROUND There have been conflicting reports on the efficacy of recombinant...

Aim: The aim of this study is to evaluate the effect of memantine on negative symptoms in patients with schizophrenia and schizoaffective. Methods: This is a double- blind randomized clinical trial. 58 patients participated in the study, 29 patients were randomly assigned to the memantine group and 29 patients to the placebo group. For assessing negative signs, and we used scale for the assess...

background: zinc is an essential trace element required for the functional activity of several enzyme systems. several studies have been carried out to assess the effect of zinc supplementation on children’s growth, but controversy exists as to the effect of zinc on growth and gh-igf-i system. objective:  the aim of this study was to evaluate the effect of zinc supplementation on linear growth ...

C Bulletin of the World Health Organization | October 2008, 86 (10) Cheung 10. YB, Zaman SM, Ruopuro ML, Enwere G, Adegbola RA, Greenwood B, et al. C-reactive protein and procalcitonin in the evaluation of the efficacy of a pneumococcal conjugate vaccine in Gambian children. Trop Med Int Health 2008;13:603-11. PMID:18331385 Direct 11. and indirect effects of routine vaccination of children with...

how to cite this article: talebian a, goudarzi rm, mohammadzadeh m , mirzadeh as. vincristine-induced cranial neuropathy. iran j child neurol. 2014 winter; 8(1):66-68.   abstract vincristine (vcr) is a vinca alkaloid that is used for treatment of many malignancies. the vinca alkaloids are neurotoxic, usually causing a peripheral neuropathy, but cranial neuropathies are rare as side effects.  de...

purpose: to evaluate the effect of oral tranexamic acid, oral prednisolone and placebo on prevention of recurrent hemorrhage in traumatic hyphema. methods: this randomized placebo-controlled double-blind clinical trial was performed on 182 subjects affected by hyphema after blunt trauma. the patients were hospitalized for at least 5 days and were randomly assigned for receiving oral tranexamic ...

A 12=week, multicenter, double-blind, randomized, placebo-controlled trial of imazodan, a type Ill phosphodiisterase inhibitor, was conducted in 147 patients with congestive heart failure to determine clinical efficacy and safety. Patients were randomized to placebo or 2,s or 10 mg of imazodan administered twice daily. Patients were maintained on their standard therapy including diuretics, digo...

1. Saoji VA. Hand, foot and mouth disease in Nagpur. Indian J Dermatol Venereol Leprol 2008;74:133-5. 2. Frydenberg A, Starr M. Hand, foot and mouth disease. Aust Fam Physician 2003;32:594-5. 3. Chang LY, Lin TY, Hsu KH, Huang YC, Lin KL, Hsueh C, et al. Clinical features and risk factors of pulmonary edema after enterovirus-71-related hand, foot, and mouth disease. Lancet 1999;354:1682-6. 4. P...