Lutesium-177 (l77Lu) merupakan salah satu radioisotop yang efektif untuk terapi kanker prostat. Radioisotop 177Lu diproduksi dengan cara mengiradiasi target Lu2O3 di teras reaktor RSG-GAS. Untuk keperluan pengendalian keselamatan iradiasi RSG-GAS, pada perlu dilakukan beberapa perhitungan, satunya adalah perhitungan perpindahan panas ke pendingin primer kolam reaktor. Panas gamma terbangkitkan ...

Peptide receptor radionuclide therapy is a type of molecular radiotherapy that has been used in the treatment patients with neuroendocrine tumours for over two decades. It not until recently, however, it achieved regulatory approval. The currently approved regimen one-size-fits-all scheme, i.e. all receive fixed activity radiopharmaceutical (177Lu-DOTATATE) and number cycles. Several research g...

objective(s): in this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. materials and methods: lu-177 of 2.6-3 gbq/mg specific activity was obtained by irradiation of natural lu2o3 sample with thermal neutron flux of 4 × 1013 n.cm-2.s-1. the product was converted into chloride form which was further used for labeling of 177lu-phytate complex and che...

A series of water-soluble chiral cyclen-based chelators with chemical handles for selective targeting have been synthesized (cyclen = 1,4,7,10-Tetraazacyclododecane). Optical studies, relaxivity measurements, and competitive titrations were performed to show the versatility these chelators. The complexations L3, L4, L5 Lu3+, Y3+, Sc3+, Cu2+ successfully demonstrated in around 90% 100% yields. E...