Abstract C 20 H 32 O 3 , monoclinic, P 2 1 (no. 4), a = 7.8981(17) Å, b 10.302(2) c 11.028(3) β 90.020(2)°, V 897.3(3) Å Z 2, R gt ( F ) 0.0603, wR ref 0.1342, T 273(2) K.

objective: β-thalassemia is caused by absence or reduction of β-globin chain synthesis. one of the effective therapeutic methods for this disease can be gene therapy by viral vectors. the capacity of lentiviral vectors is approximately 8 kb, we designed a 6 kb construct containing mini lcr and β-globin gene instead of lcr region. the aim of this study is to make a recombinant lentiviruses conta...

Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Emerging data suggests that T helper 17 (Th17) cells play a pathogenic role in SLE and the increased number of these cells correlates with disease activity. In recent years, 1α, 25-dihydroxyvitamin D3 (1,25VitD3) has been considered as an immunomodulatory factor. Objective: To investigate the effect of 1,25VitD3...

Three new steroidal glycosides, cyanoauriculosides F, G and H (1-3), were isolated from the roots of Cynanchum auriculatum (Asclepiadaceae) along with two known steroidal derivatives. On the basis of spectroscopic analysis and chemical methods, their structures were identified as 20-O-acetyl-8,14-seco-penupogenin-8-one 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-diginopyranosyl-...

Abstract C 36 H 26 N 4 O 5 Co, monoclinic, 2/ c (no. 15), a = 29.3826(17) Å, b 10.3153(5) 19.9407(12) β 107.263(6), V 5771.6(6) Å 3 , Z 8, R gt ( F ) 0.0341, w ref 2 0.0777, T 200 K.

Abstract C 12 H 9 Cl F N 3 , monoclinic, P 2 1 / n (no. 14), a = 10.120(4) Å, b 13.823(6) c 16.480(7) β 91.744(8)°, V 2304.4(17) Å Z 8, R gt ( ) 0.0402, wR ref 0.0932, T 113.15 K.