Almost all animals contain mitochondria of maternal origin only, but the exact mechanisms underlying this phenomenon are still vague. We investigated the fate of Drosophila paternal mitochondria after fertilization. We demonstrate that the sperm mitochondrial derivative (MD) is rapidly eliminated in a stereotypical process dubbed paternal mitochondrial destruction (PMD). PMD is initiated by a n...

Thyrotropin-releasing hormone (TRH) stimulated a rapid rise in inositol trisphosphate (IP3) formation and prolactin release from 7315c tumor cells. The potencies (half-maximal) of TRH in stimulating IP3 formation and prolactin release were 100 +/- 30 and 140 +/- 30 mM, respectively. Pretreatment of the cells with pertussis toxin (for up to 24 h) had no effect on either process. Pretreatment of ...

Studies of the various kinds of immunoglobulin (Ig) allotype and isotype suppressions induced by perinatal exposure to anti-Ig antibodies have yielded many valuable insights into the normal processes that control B cell differentiation and expression. For example, the demonstration that exposure to antibodies to an IgG isotype specifically suppresses production of that isotype, whereas the expo...

The purpose of this study was to determine the quality of fresh and cooked meat, and the nutritive value of this meat from 62 male Australian feral goats. The goats were slaughtered at 5, 10, 20, 30, 40, 50, 60 and 70kg liveweights. Half of the goats were castrated and half were left as intact animals. The quality profiles of meat (e.g. pH, colour, pigment concentrations, cooking loss, shear fo...

low water consumption in autumn sugar beet sowing is an important strategy for sugar beet production, especially in arid regions like iran. for the development of a new monogerm triploid hybrid called sharif which is bolting tolerant and suitable for autumn sowing in khuzestan province, a breeding program was started in 1994 and continued for16 years. this program had two stages; the first stag...

BACKGROUND Paternal preconception risk factors such as smoking, exposure to environmental substances, medication use, overweight and advanced age correlate with the occurrence of malformations and birth defects in the offspring. Nonetheless, the prevalence of risk factors for adverse pregnancy outcomes in the male population has been scarcely investigated and no report on preconception interven...

Human mitochondrial DNA (mtDNA) is a 16.5-kb, circular genome essential for the maintenance of mitochondrial function and is present in multiple copies in most cell types. High sequence divergence and maternal inheritance make mtDNA useful in tracing human lineages. Whether recombination occurs between mitochondrial genomes is a longstanding question in mitochondrial biology, human evolution, a...