A crystal structure of the bacteriophage T7 gene 5 protein/Escherichia coli thioredoxin complex reveals a region in the exonuclease domain (residues 144-157) that is not present in other members of the E. coli DNA polymerase I family. To examine the role of this region, a genetically altered enzyme that lacked residues 144-157 (T7 polymerase (pol) Delta144-157) was purified and characterized bi...

The cancer-testis antigen NY-ESO-1 is one of the most promising candidates for generic vaccination of cancer patients. Here we analyzed the CD8(+) T cell response to a NY-ESO-1 peptide vaccine composed of the two previously defined peptides 157-165 and 157-167, administered with GM-CSF as a systemic adjuvant. The NY-ESO-1 peptide vaccine elicited a CD8(+) T cell response directed against multip...

Arteriogenesis is an inflammatory process associated with rapid cellular changes involving vascular resident endothelial progenitor cells (VR-EPCs). Extracellular cell surface bound 20S proteasome has been implicated to play an important role in inflammatory processes. In our search for antigens initially regulated during collateral growth mAb CTA 157-2 was generated against membrane fractions ...

Bottom anti-reflective coatings (BARCs) are essential for achieving the 65-nm node resolution target by minimizing the substrate reflectivity to less than 1% and by planarizing substrates. We believe that the developments in 157-nm BARC products are on track to make them available for timely application in 157-nm lithography. We have made some significant improvements in resist compatibility an...

Sanderson [12] gave an isomorphism θ : πm(∨ r i=1S 2 i ) −→ πm(∨ r+1 i=1 CP∞ i ). In this paper we construct for any subset σ ⊂ {1, 2, · · · , r} an isomorphism θσ from πm(∨ r i=1S 2 i ) to πm(∨ r+1 i=1 CP∞ i ). The inclusion S ∨ S →֒ CP∞ ∨ CP∞ induces a homomorphism f : πm(S 2 ∨ S) −→ πm(CP ∞ ∨ CP∞). We also compute f by evaluating f on each factor in the Hilton splitting of πm(S 2 ∨ S), the re...

Kubik A, Polak J. Lung cancer detection: results of a random¬ ized prospective study in Czechoslovakia. Cancer 1986; 57: 2428-37 6 Muhm JR, Miller EW, Fontana RS, et al. Lung cancer detected during a screening program using four-month chest radiographs. Radiology 1983; 148:609-15 7 Fontana R, Sanderson DR, Woolner LB, et al. Screening for lung cancer: a critique of the Mayo Lung Project. Cancer...

Ph.D. thesis (European doctorate mention) in Computer Science written by Davide Buscaldi under the supervision of Dr. Paolo Rosso (Univ. Politécnica de Valencia). The author was examined in Valencia in October 2010 by a panel composed by the following doctors: Paul David Clough (University of Sheffield), Ross Purves (Universität Zürich), Emilio Sanchis Arnal (Univ. Politécnica de Valencia), Mar...

With the introduction of 157 nm as the next optical lithography wavelength, the need for new pellicle and photoresist materials optimized for this wavelength has produced much activity in optical characterization of thin film materials. Here we focus on ultratransparent fluoropolymers for 157 nm pellicle applications where absorbances below 0.01/μm are necessary to achieve transmissions above 9...