BACKGROUND Most cases of hyponatremia--serum sodium concentration ([Na+]) < 135 mEq/l (< 135 mM)--are associated with an elevated plasma arginine vasopressin level. This study investigated the efficacy and tolerability of intravenous conivaptan (YM087), a vasopressin V1A/V2-receptor antagonist, in treating euvolemic and hypervolemic hyponatremia. METHODS Eighty-four hospitalized patients with...

The high nutritional content in catfish oil can be a rich source of omega-3 fatty acids, which function the development child's brain. However, acid causes fish to become more susceptible oxidation during storage process, prevented by adding antioxidants. This study aims determine quality after ginger as an antioxidant. method used is titration peroxide value and number free acids. results obta...

The effects of SCH 34826, an orally active neutral metalloendopeptidase inhibitor, on responses to atrial natriuretic factor-(103-125) or -(99-126) and on blood pressure were evaluated in rats. SCH 34826 (10, 30, and 90 mg/kg s.c. and 90 mg/kg p.o.) potentiated the antihypertensive action of atrial natriuretic factor (30 micrograms/kg i.v.) in conscious spontaneously hypertensive rats. SCH 3482...

STUDY OBJECTIVE To determine the efficacy of outpatient rapid i.v. rehydration in correcting dehydration and resolving vomiting in children with mild to moderate dehydration resulting from acute gastroenteritis. METHODS We carried out a prospective cohort study in an urban children's hospital. A convenience sample of 58 children aged 6 months to 13 years, with acute gastroenteritis and clinic...

Nineteen patients with normal renin idiopathic hypertension were arbitrarily classified as salt-sensitive or salt-resistant depending on whether their mean arterial pressure did or did not increase by 8% or more when sodium intake was increased. The responses of the two subsets and of five normal subjects to sodium intakes of 9, 109, and 249 mEq/day given for 7 days were as follows: The salt-se...

In isolated fiber bundles of external intercostal muscle from each of 13 normal volunteers and each of 6 patients with myotonia congenita, some or all of the following were measured: concentrations of Na(+), K(+), and Cl(-), extracellular volume, water content, K(+) efflux, fiber size, fiber cable parameters, and fiber resting potentials. Muscle from patients with myotonia congenita differed si...

A 15-week-old, male intact, 9.8 kg English Bulldog presented to the University of Georgia Veterinary Teaching Hospital (VTH) for surgical correction of presumed brachycephalic airway syndrome. For 3 weeks before admission, the dog experienced stertorous breathing that was not responsive to antibiotic treatment, including doxycycline, cefpodoxime, and marbofloxacin, for treatment of presumptive ...