A general strategy for fast decarboxylative difunctionalization to gem-dihalohydrin, gem-dihaloether, gem-dibromoester and cyclized bromo-1,4-dioxane synthons with outstanding regio- and stereoselectivity is demonstrated.

The structure of the complex formed between 1,4 dioxane and iodine monochloride has been studied as a function pressure using neutron powder diffraction. Initial compression was accompanied by a...

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 5H-dibenzo[a,d]cyclo-hepta-triene-5-carboxamide-1,4-dioxane (2/1)], 2C(16)H(13)NO·C(4)H(8)O(2), the cytenamide mol-ecules form a hydrogen-bonded R(2) (2)(8) dimer. The solvent mol-ecule is located between two adjacent cytenamide dimers and forms N-H⋯O hydrogen bonds with one cytenamide mol-ecule from each dimer.

Co-contamination with chlorinated compounds and 1,4-dioxane has been reported at many sites. Recently, there an increased interest in bioremediation because of the potential to degrade multiple contaminants concurrently. Towards improving efficacy, current study examined laboratory microcosms (inoculated separately two soils) determine phylotypes functional genes associated biodegradation commo...

Nucleophilic ring opening of dl and meso 1,1¢- dicyclohexenyl diepoxides by sodium azide in dioxane and aqueous alcoholic medium give the corresponding azidoalcohols. The obtention of departure diepoxides from diazidoalcohols by the reaction with sodium hydride shows the anti position of OH and N3 groups.

Carbohydrate moieties are important components of natural products, which are often imperative for the solubility and biological activity of the compounds. The aromatic polyketide alnumycin A contains an extraordinary sugar-like 4'-hydroxy-5'-hydroxymethyl-2',7'-dioxane moiety attached via a carbon-carbon bond to the aglycone. Here we have extensively investigated the biosynthesis of the dioxan...

Solvatochromic shifts of the electronic states of a chromophore can be used as a measure of solute-solvent interactions. The shifts of the electronic states of a model organic chromophore, p-nitroaniline (pNA), embedded in solvents with different polarities (water, 1,4-dioxane, and cyclohexane) are studied using a hybrid quantum mechanics/molecular-mechanics-type technique in which the chromoph...