The use of human urine as a diagnostic tool has many advantages, such as ease of sample acquisition and noninvasiveness. However, the discovery of novel biomarkers, as well as biomarker patterns, in urine is hindered mainly by a lack of comparable datasets. To fill this gap, we assembled a new urinary fingerprint database. Here, we report the establishment of a human urinary proteomic fingerpri...

AIMS The molecular epidemiological studies on the association of the opioid receptor µ-1 (OPRM1) polymorphism A118G (Asn40Asp, rs1799971) and alcohol use disorders have given conflicting results. The aim of this study was to test the possible association of A118G polymorphism and alcohol use disorders and alcohol consumption in three large cohort-based study samples. METHODS The association b...

BACKGROUND Indoor air pollution remains an important health problem in some countries. Although research data on this issue is available, routine monitoring in affected areas is limited. The aims of this study were to quantify exposure to biomass-related indoor air pollution; assess the respiratory health of subjects; and explore the feasibility of routine monitoring in Kwale district, Kenya. ...

We hypothesized that the presence of monoclonal free kappa or lambda immunoglobulin light chains in monoclonal gammopathy of undetermined significance (MGUS), as detected by the serum free light chain (FLC) assay increases the risk of progression to malignancy. Of 1384 patients with MGUS from Southeastern Minnesota seen at the Mayo Clinic from 1960 to 1994, baseline serum samples obtained withi...

Received: January 4, 2016 • Revised: February 12, 2016 • Accepted: February 12, 2016 Corresponding Author: Myung Jin Lee (http://orcid.org/0000-0001-9076-7771) 1384 Nambusunhwan-ro, Geumcheon-gu, Seoul 08547, Korea Tel: +82.10.5259.5795 Fax: +82.2.865.5527 email: [email protected] Korean J Med Educ 2016 Jun; 28(2): 153-156. http://dx.doi.org/10.3946/kjme.2016.27 eISSN: 2005-7288 C The Korean...

BACKGROUND Less than half of U.S. adults engage in the recommended amount of physical activity (PA). Internet-delivered PA programs increase short-term PA but long-term adherence is largely equivocal. PURPOSE To determine whether increased PA following the 16-week Internet-delivered Active Living Every Day (ALED-I) program is maintained 8 months later in sedentary and overweight rural adults....

Scattering by interstellar dust grains can produce time variable X-ray halos around gamma-ray bursts (GRB). In particular, an X-ray expanding ring is expected when a short pulse of X-ray radiation is scattered by a narrow layer of dust in our Galaxy. We present a new method to detect and analyze dust scattering expanding rings around gamma-ray bursts, using as an example XMM-Newton data of GRB ...

BACKGROUND It is well known that atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with a higher risk of stroke, and new evidence links AF to cognitive impairment, independently from an overt stroke (CI). Our aim was to investigate, assuming an underlying role of atrial microembolism, the impact of CI and CKD in elderly hospitalized patients with AF. METHODS We retrospe...