Review of the MEDLINE, Embase, Web Science, and Cochrane databases through February 1, 2021. There were 1348 patients from 14 eligible studies (10 prospective, randomized; 4 retrospective) with femoropopliteal artery in-stent restenosis (FP-ISR) who underwent plain old balloon angioplasty (POBA), drug-coated (DCBA), peripheral cutting angioplasty, Viabahn endoprosthesis, directional atherectomy...

The Front Cover shows the Karlštejn Castle, a large Gothic castle founded in 1348 by Charles IV, Holy Roman Emperor-elect and King of Bohemia (and founder University Prague). served as place for safekeeping Imperial well Bohemian crown jewels, holy relics, other royal treasures. From synthetic chemist's point view, chiral ligands enabling high asymmetric inductions can be also considered jewels...

We present near-infrared spectroscopic observations of SN 1987A covering the period 1358 to 3158 days post-explosion. This is the first time that IR spectra of a supernova have been obtained to such late epochs. The spectra comprise emission from both the ejecta and the bright, ring-shaped circumstellar medium (CSM). The most prominent CSM emission lines are recombination lines of H I and He I,...

Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel belonging to the adenosine triphosphate (ATP)-binding cassette (ABC) superfamily. ABC proteins share a common molecular mechanism that couples ATP binding and hydrolysis at two nucleotide-binding domains (NBDs) to diverse functions. This involves formation of NBD dimers, with ATP bound at two composite interfacial ...

We consider a continuous-time variant of the classical Economic Lot-Sizing (ELS) problem. In this model, the setup cost is a continuous function with lower bound Kmin > 0, the demand and holding costs are integrable functions of time and the replenishment decisions are not restricted to be multiples of a base period. Starting from the assumption that certain operations involving the setup and h...

1 diSPAA, Animal Science Section. University of firenze, via delle Cascine, 5, IT-50144 firenze 2 Corresponding author, e-mail: [email protected] 3 Agricultural Institute of Slovenia, hacquetova ul. 17, SI-1000 Ljubljana 4 Cnr-Institute for Microelectronics and Microsystems, via del fosso del Cavaliere, IT-00100 roma 5 InrA, UMr 1348 Pegase, f-35590 Saint-gilles, france; Agrocampus Oue...

It is well documented that human epidermal growth factor receptor 2 (HER2) overexpression/amplification is associated with poor survival in breast cancer patients. However, it is largely unknown whether HER2 somatic mutations are associated with survival in HER2-negative breast cancer patients. Here, we identified HER2 somatic mutations in tumors from 1348 unselected breast cancer patients by s...