نتایج جستجو برای: 13 dicarbonyl

تعداد نتایج: 333355  

Journal: :Bioscience, Biotechnology, and Biochemistry 2012

Journal: :Molecular nutrition & food research 2008
Elvira Mavric Silvia Wittmann Gerold Barth Thomas Henle

The 1,2-dicarbonyl compounds 3-deoxyglucosulose (3-DG), glyoxal (GO), and methylglyoxal (MGO) were measured as the corresponding quinoxalines after derivatization with orthophenylendiamine using RP-HPLC and UV-detection in commercially available honey samples. Whereas for most of the samples values for 3-DG, MGO, and GO were comparable to previously published data, for six samples of New Zealan...

2014
Norbert Nass Hans-Jürgen Brömme Roland Hartig Sevil Korkmaz Saadettin Sel Frank Hirche Aoife Ward Andreas Simm Stefan Wiemann Anne E. Lykkesfeldt Albert Roessner Thomas Kalinski

Tamoxifen is the standard adjuvant endocrine therapy for estrogen-receptor positive premenopausal breast cancer patients. However, tamoxifen resistance is frequently observed under therapy. A tamoxifen resistant cell line has been generated from the estrogen receptor positive mamma carcinoma cell line MCF-7 and was analyzed for putative differences in the aldehyde defence system and accumulatio...

Journal: :SynOpen 2021

Abstract A highly efficient and catalyst-free protocol is reported for the synthesis of quinoxalines via classical cyclocondensation reaction between aryldiamines dicarbonyl compounds. Remarkably simple green conditions employing methanol as solvent afforded medium to excellent yield after only one-minute time at ambient temperature. The allow least 10 gram scale should be a preferred starting ...

Journal: :Biomedicine and chemical sciences 2022

Nine copolyesters were prepared from a dicarboxylic acid, curcumin analogues (monocarbonyl) and phenophthalene dye in the mole ratio of 2:1:1 by direct polycondensation using triethylamine (Et3N) as condensation agent. The used is 2,6-Pyridine dicarbonyl dichloride acid. acid catalyzed Aldol reaction. These characterized FT-IR. fluorescence synthesized was also investigated. Furthermore, Thermo...

2010
Paul J. Thornalley Sahar Waris Thomas Fleming Thomas Santarius Sarah J. Larkin Brigitte M. Winklhofer-Roob Michael R. Stratton Naila Rabbani

Glyoxal and methylglyoxal are reactive dicarbonyl metabolites formed and metabolized in physiological systems. Increased exposure to these dicarbonyls is linked to mutagenesis and cytotoxicity and enhanced dicarbonyl metabolism by overexpression of glyoxalase 1 is linked to tumour multidrug resistance in cancer chemotherapy. We report herein that glycation of DNA by glyoxal and methylglyoxal pr...

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