Recurrent chromosome 11q23 abnormalities, including focal gains and losses have been described in mantle cell lymphoma, diffuse large B-cell lymphoma (DLBCL) and in a subset of high-grade B-cell lymphomas lacking MYC rearrangements. We describe a novel fusion of FOXR1 forkhead box gene, located at 11q23, with a neighboring gene in B-cell lymphoma. RNAseq and sequencing of cloned PCR products re...

We report on two patients who developed a secondary acute myeloid leukemia (sAL) after treatment for non-Hodgkin's lymphoma (NHL) with regimens containing low to intermediate doses of VP16. Clinical and hematologic features in these two patients were consistent with epipodophyllotoxin-associated sAL. In one case, a rearrangement of chromosome band 11q23 was detected.

BACKGROUND AND OBJECTIVES Human leukemia cell lines are of great value in leukemia research. Thus far 36 leukemia cell lines carrying the 11q23 translocation and MLL rearrangements, including two cell lines with t(6;11)(q27;q23) and an MLL-AF6 fusion gene have been described. We have established a new monocytic cell line with t(6;11), designated SHI-1, and herein describe its biological charact...

iranian cave barb (iranocypris typhlops, bruun and kaiser, 1944)is one of thevery rareandendemicspeciesof iran. its distributionrangeislimitedina habitat that causes some problems for its conservation. thisuniquehabitatfaces somenatural and humanthreatsand the habitatdestructionmeansthe extinctionof the species. based on, habitat selection for translocation of the species is an important object...

The predictive value of HLA-DR and CD34 in the diagnosis of four distinct genetic entities of acute myeloid leukemia (AML) is presently not established. We evaluated the positive and negative predictive values (PPV and NPV, respectively), sensitivity, specificity, and correlation coefficients of HLA-DR and CD34 in AML patients with t(15;17), t(8;21), inv(16), and abn(11q23). In AML with t(15;17...

a cytogenetic study was performed on 11 tetraploid cotton cultivars (gossypium hirsutum l.)including the oltan cultivar and its crossing progenies. the chromosome pairing and chiasma frequency, aswell as meiotic abnormalities were compared among the genotypes studied. heterozygote translocations withalternate orientation were observed between some of the chromosomes of the a genome and those of...

this paper provides information on the geographic distributions of two cyprinid species: hemiculter leucisculus (basilewsky, 1855) and alburnus caeruleus heckel, 1843, in the world and the entire drainage systems in iran. the new distribution records were taken from maroon river (jarrahi river system) and chardaval river (karkheh river system), both in tigris river basin showing wide and narrow...

abstract chromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. although x-autosome translocations are frequently associated with streak gonads and clinical features of the turner syndrome, the majority of x-autosome carriers may present with a variable phenotype, developmental delay, and recognizable x-linked syndrome...

 Introduction: Bacterial translocation is defined as the passage of bacteria from intestinal tract to the extraintestinal organs such as the peritoneum and blood circulation. The aim of this study is to examine bacterial translocation (regarding type of bacteria and effect of time of obstruction on bacterial translocation) from intestinal lumen to the peritoneum and viscera in acute, simple mec...