Intraarterial administration of 40-/um degradatale starch microspheres (DSM) in a drug solution can temporarily retard flow of the drug-blood column through the arteriolar-capillary bed and lead to increased local drug deposition. Premonitory to Phase IIIII efficacy studies applying this concept to regional therapy, it was necessary to determine the DSM dose to use. Patients with hepatic cancer...

Several revisions to the symptom clusters of posttraumatic stress disorder (PTSD) have been made in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Central to the focus of this study was the revision of PTSD's tripartite structure in DSM-IV into four symptom clusters in DSM-5. Emerging confirmatory factor analytic (CFA) studies have suggested that DSM-5 PTS...

We propose a novel direct sampling method (DSM) for the effective and stable inversion of Radon transform. The DSM is based on generalization important almost orthogonality property in classical DSMs to fractional order Sobolev duality products new family probing functions. product proves be able greatly enhance robustness reconstructions some practically but severely ill-posed inverse problems...

The large-conductance voltage- and Ca(2+)-activated K(+) (BK) channel is expressed in many smooth muscle types, but its role in human detrusor smooth muscle (DSM) is unclear. With a multidisciplinary approach spanning channel molecules, single-channel activity, freshly isolated human DSM cells, intact DSM preparations, and the BK channel specific inhibitor iberiotoxin, we elucidated human DSM B...

Diagnostic and Statistical Manual (DSM-5) criteria for ASD have been criticized for being too restrictive, especially for more cognitively-able individuals. It is unclear, however, if high-functioning individuals deemed eligible for research via standardized diagnostic assessments would meet DSM-5 criteria. This study investigated the impact of DSM-5 on the diagnostic status of 498 high-functio...

Since the first edition of the Diagnostic and Statistical Manual: Mental Disorders was published in 1952 by the American Psychiatric Association (APA), the manual has gone through a series of revisions: DSM-II in 1968, DSM-III in 1980, DSM-IIIR in 1987, DSM-IV in 1994, and a text revision to the DSM-IV in 2000. For those with a sharp eye, one will note that, subsequent to DSM-I, the manual has ...

This paper presents the design and implementation issues for the use of DSM techniques to allow shared access to objects in an object-oriented distributed environment. J-DSM supports sharing of Java objects, thus allowing a finer control over the granularity of sharing. J-DSM elaborates on two main classes of shared objects, mobile and stationary, which can be accessed through DSM and RMI mecha...

This paper aims to interpret Demand-Side Management (DSM) activity and to point out its problems, adopting micro economics as an analytical tool. Two major findings follow. First, the cost-benefit analysis currently in use has the following problems: (i) inconsistency in cost comparison between utility costs on the supply-side and utility costs plus customer costs on the demand-side, (ii) incon...