The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. The underlying ubiquitin-dependent proteolytic system, called the N-end rule pathway, is organized hierarchically: N-terminal aspartate and glutamate (and also cysteine in metazoans) are secondary destabilizing residues, in that they function through their conjugation, by arginyl-tRNA-protein tr...

The decline of N from N-labelled mature pea residues was followed in unplanted soil over 16.5 yr. Eight years after residue incorporation, 24% of the residue N input was still present in the soil and, after 16.5 yr, 16% of the residue N input remained. A double exponential model successfully described the decay of N from N-labelled pea residues. The total residual N declined with average decay ...

Quadratic theory of gravity is a complicated constraint system. We investigate some consequences of treating quadratic terms perturbatively (higher derivative version of backre-action effects), which is consistent with the way existence of quadratic terms was originally established (radiative loop effects and renormalization procedures which induced quadratic terms). We show that this approach ...

It is now well established that accommodation adopts an intermediate resting position in the absence of visual stimulation. It also has been shown that this tonic position of accommodation exhibits considerable variation among individuals (ie, 0-4 D). Previous studies have been somewhat inconclusive as to whether these individual differences in tonic accommodation are related to the refractive ...

The pyrolysis of two types of tobacco residue was carried out at different pyrolysis temperatures between 300 and 600 °C and a residence time of 1 h in a nitrogen atmosphere. The effect of pyrolysis temperature on the product distributions was investigated and the composition of the bio-oils identified. The variation in product distribution depended on both the temperature and the type of tobac...

Homology models of cytochrome P450 2D6 (CYP2D6) have identified serine 304 as an active-site residue and implicated a putative role for this residue in substrate enantioselectivity and the differential inhibition of enzyme activity by the diastereoisomers quinine and quinidine. The role of serine 304 in selectivity is thought to be achieved through a preferential hydrogen-bond interaction betwe...

the aim of this study was investigation the energy flow and global warming potential (gwp) of corn farm in gorgan city. for this purpose, data were collected from three conventional planting methods (spring planting, summer planting in wheat residue and summer planting without wheat residue) by using a face-to-face questionnaire performed with farmers in summer 2012. after the required data in ...

In this paper, a decoding method is proposed for the (41, 21, 9) quadratic residue code. The method is acquired through applying the condition of the modified Gao’s algorithm that is similar to fast transform decoding developed by Shiozaki [8]. The property of the syndrome polynomial is used in our decoding method. The new algorithm for has been verified by a software simulation using C languag...

Two T cell clones derived from different donors with HLA-DRB1*0403 or DRB1*0901 phenotype recognize a rubella capsid peptide, C(265-273) in the context of several different HLA-DR molecules in addition to DRB1*0403 and DRB1*0901. All DR molecules restricting the T-cell clones have in common residues, R or Q at position beta 70, R at position beta 71, and E at position beta 74 in pocket '4' of t...