نتایج جستجو برای: 0235 and 043
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Classical string cosmology consists of two branches related to each other by scale-factor duality: a super-inflation branch and a Friedmann-RobertsonWalker (FRW) branch. Curvature and string coupling singularity separates the two branches, hence posing ‘graceful exit problem’ to super-inflationary string cosmology. In an exactly soluble two-dimensional compactification model it is shown that qu...
as its first research and training centre and started work in Helsinki, Finland in 1985. The Institute undertakes applied research and policy analysis on structural changes affecting the developing and transitional economies, provides a forum for the advocacy of policies leading to robust, equitable and environmentally sustainable growth, and promotes capacity strengthening and training in the ...
Zimbabwe's HIV epidemic is amongst the worst in the world, and disproportionately effects poorer rural areas. Access to almost all health services in Zimbabwe includes some form of cost to the client. In recent years, the socio-economic and employment status of many Zimbabweans has suffered a serious decline, creating additional barriers to HIV treatment and care. We aimed to assess the impact ...
Purpose: The purpose of our research is to determine the protective impact CoronaVac vaccine in individuals under age 40 and over 18 who have had COVID-19 infection.
 Material Methods: Patients aged 18-40 years applied hospital with + as a test were divided into two groups according their coronaVac status, morbidity mortality patients investigated.
 Results: In present research, total...
The benzothiazinone lead compound, BTZ043, kills Mycobacterium tuberculosis by inhibiting the essential flavo-enzyme DprE1, decaprenylphosphoryl-beta-D-ribose 2-epimerase. Here, we synthesized a new series of piperazine-containing benzothiazinones (PBTZ) and show that, like BTZ043, the preclinical candidate PBTZ169 binds covalently to DprE1. The crystal structure of the DprE1-PBTZ169 complex re...
A series of 8-nitro-6-(trifluoromethyl)-1,3-benzothiazin-4-ones (BTZs) bearing an oximido or amino nitrogen heterocycle moiety through modifications at the C-2 position of BTZ043 and BPTZ169 were designed and synthesized as new antitubercular agents. Many of the target compounds demonstrate excellent in vitro activity (MIC: <0.016–0.088 mg mL ) against the drug susceptive H37Rv strain and two c...
El objetivo del presente trabajo fue investigar la eficacia de un programa intervención seis semanas duración basado en el entrenamiento habilidades psicológicas y mindfulness control estrés, influencia evaluación rendimiento, motivación, habilidad mental cohesión equipo jóvenes jugadoras voleibol. Participaron estudio 10 voleibol entre 13 16 años (M = 14.40; DT .84), quienes fueron asignadas f...
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