BACKGROUND Recurrent medulloblastoma is a therapeutic challenge because it is almost always fatal. Studies have confirmed that medulloblastoma consists of at least four distinct subgroups. We sought to delineate subgroup-specific differences in medulloblastoma recurrence patterns. METHODS We retrospectively identified a discovery cohort of all recurrent medulloblastomas at the Hospital for Si...

OBJECTIVES To determine and compare the cost-effectiveness of implementing 3 screening strategies to detect human immunodeficiency virus (HIV) infection among pregnant women in Chicago, Illinois: no screening, voluntary screening, and universal screening. METHODS A decision-analysis model was developed, using standard cost-effectiveness analysis from a societal perspective. Reference case est...

Kykyri, Virpi-Liisa Helping Clients to Help Themselves. A Discursive Perspective to Process Consulting Practices in Multi-party Settings Jyväskylä, University of Jyväskylä, 2008, 76 p. (Jyväskylä Studies in Education, Psychology and Social Research ISSN 0075-4625; 330) ISBN 978-951-39-3082-0 (PDF), 978-951-39-3071-4 (nid.) Finnish Summary Diss. This study approaches process consulting work as c...

Personhood is a foundational concept in ethics, yet defining criteria have been elusive. In this article we summarize attempts to define personhood in psychological and neurological terms and conclude that none manage to be both specific and non-arbitrary. We propose that this is because the concept does not correspond to any real category of objects in the world. Rather, it is the product of a...

HomePlant DiseaseVol. 105, No. 12First Report of Fusarium commune Causing Root and Crown Rot on Maize in Italy PreviousNext DISEASE NOTE OPENOpen Access licenseFirst ItalyM. Mezzalama, V. Guarnaccia, I. Martino, G. Tabone, M. L. GullinoM. Mezzalama†Corresponding author: Mezzalama; E-mail Address: [email protected]://orcid.org/0000-0003-2558-8878AGROINNOVA – Centre Competence for th...

THE INVESTIGATION of biological systems such as the lung can be thought of as proceeding through a series of stages. The first stage is observational, involving the cataloguing of structures, patterns and behaviors that impinge on our everyday experience at the macroscopic level. This leads to the initial formulation of hypotheses about what might be underlying such behavior, and is most readil...

Directionally controlled self-assembly of multiple molecules is an important technique for constructing multidimensional structures. DNA molecules are widely used for controlled self-assembly because of their programmability, defined structure, and acceptance of various functionalizations. The scaffolded DNA origami method developed for the preparation of twodimensional (2D) structures has been...

AIRWAY HYPERRESPONSIVENESS is a hallmark feature of asthma and is defined as an excessive decrement in lung mechanical function following challenge with standard doses of a smooth muscle agonist, such as methacholine. Accordingly, understanding the mechanisms underlying airway hyperresponsiveness is seen as central to understanding the pathogenesis of asthma itself. Here is where things get com...

The Agency for Healthcare Research and Quality (AHRQ), formerly the Agency for Health Care Policy and Research (AHCPR), sponsors and conducts research that provides information on health care outcomes, quality, cost, use, and access. The information helps health care decision makers—patients and clinicians, health system administrators, and policy makers—to make more informed decisions in order...