نتایج جستجو برای: 002 to 045

تعداد نتایج: 10617876  

2013
N Mkrtchyan G Amaryan N Aghababyan K Mirzabekyan T Sarkissian

Methods We observed 2300 patients with FMF (1408 boys and 892 girls; mean age: 8.86±0.29) in the National Pediatric Centre for FMF. Diagnosis of FMF was based on Tel-Hashomer criteria and MEFV genetic analysis. The epilepsy was diagnosed based on clinical manifestations (>2 unprovoked epileptic seizures),neurological history, exam, EEG and MRI. The statistical analysis was performed using Epi-I...

1996
L. E. GORDON

We study the expectations for prompt photon production rates at HERA in a fully consistent next-to-leading order (NLO) QCD analysis, taking into account the effects of experimental isolation requirements. In particular we examine the sensitivity of the isolated cross section to the photon's gluon content. The utility of hadronic large-p T prompt photon production for providing constraints on th...

2011
James A. Kurien Brian C. Williams

Space missions have historically relied upon a large ground staff, numbering in the hundreds for complex missions, to maintain routine operations. When an anomaly occurs, this small army of engineers attempts to identify and work around the problem. A piloted Mars mission, with its multiyear duration, cost pressures, half-hour communication delays and two-week blackouts cannot be closely contro...

2017
Mirela Paiva Vasconcelos-Moreno Gabriel Rodrigo Fries Carolina Gubert Bárbara Tietböhl Martins Quadros dos Santos Adam Fijtman Juliana Sartori Pamela Ferrari Lucas Kich Grun Mariana Migliorini Parisi Fátima Theresinha Costa Rodrigues Guma Florencia Maria Barbé-Tuana Flávio Kapczinski Adriane Ribeiro Rosa Lakshmi N. Yatham Marcia Kauer-Sant’Anna

Background Growing evidence supports the existence of neurobiological trait abnormalities in individuals at genetic risk for bipolar disorder. The aim of this study was to examine potential differences in brain-derived neurotrophic factor, cytokines, oxidative stress, and telomere length markers between patients with bipolar disorder, their siblings, and healthy controls. Methods Thirty-six p...

Journal: :Expert Opinion on Investigational Drugs 2008

2002
S. Gerber F. Joos P. Brügger T. F. Stocker M. E. Mann S. Sitch

The response of atmospheric CO2 and climate to the reconstructed variability in solar irradiance and radiative forcing by volcanoes over the last millennium is examined by applying a coupled physical-biogeochemical climate model that includes the Lund-Potsdam-Jena dynamic global vegetation model (LPJ-DGVM) and a simplified analogue of a coupled atmosphere-ocean general circulation model. The mo...

2008
Danyelle M. Townsend Lin He Steven Hutchens Tracy E. Garrett Christopher J. Pazoles Kenneth D. Tew

NOV-002 is a novel glutathione disulfide mimetic that when administered in combination with standard chemotherapeutic regimens has resulted in increased efficacy (survival, tumor response) and improved tolerance to chemotherapy (e.g., hematologic recovery) in advanced non–small cell lung cancer patients. We show that NOV-002, which is not cytotoxic as a single agent, generated timeand concentra...

Journal: :Cancer research 2008
Danyelle M Townsend Lin He Steven Hutchens Tracy E Garrett Christopher J Pazoles Kenneth D Tew

NOV-002 is a novel glutathione disulfide mimetic that when administered in combination with standard chemotherapeutic regimens has resulted in increased efficacy (survival, tumor response) and improved tolerance to chemotherapy (e.g., hematologic recovery) in advanced non-small cell lung cancer patients. We show that NOV-002, which is not cytotoxic as a single agent, generated time- and concent...

2015
Jamie L. Schafer Moritz Ries Natasha Guha Michelle Connole Arnaud D. Colantonio Emmanuel J. Wiertz Nancy A. Wilson Amitinder Kaur David T. Evans Guido Silvestri

Natural killer (NK) cell responses in primates are regulated in part through interactions between two highly polymorphic molecules, the killer-cell immunoglobulin-like receptors (KIRs) on NK cells and their major histocompatibility complex (MHC) class I ligands on target cells. We previously reported that the binding of a common MHC class I molecule in the rhesus macaque, Mamu-A1*002, to the in...

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