* لوئسم هدنسيون : فيرـش نابايخ ،ناهفصا يوـك ،يـفقاو نب ،يناطلس نسحم ديهش حرف تسب كلاپ ،شخب 10 / 8 نفلت : 3168058 0913 email: [email protected] فده و هنيمز : ميزنآ نيرتمهم زا زانژيسكا ولكيس ميزنآ نيدنلاگاتسورپ زتنس ريسم ياه ا شياديپ و اه ندب رد باهتل تسا ناسنا . هزات رد رثا تاقيقحت نيرت ت رخ ي زانژيسكا ولكيس ميزنا زا يب 2 لولس رب هدش هديد ناسنا زغم يبصع ياه ب تسا ه يروط...

Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 (transient receptor potential vanilloid subtype 1) agonist with significant initial transient hyperalgesia followed by a prolonged analgesic effect in response to thermal stimulus. Using a rat model of neuropathic pain, we evaluated the effect of pretreatment with clonidine-which has been shown to relieve intradermal capsaicin-induced hype...

OBJECTIVE To compare the approved treatment of rheumatoid arthritis using rituximab + methotrexate (RTX + MTX) versus the off-label treatment variants of RTX in monotherapy or RTX in combination with leflunomide (RTX + LEF). METHODS We included RTX-naive patients enrolled in the German biologics register RABBIT (Rheumatoid Arthritis: Observation of Biologic Therapy) between 2007 and 2012 (n =...

مداخل يعسوت رامعم ميمصت " ةجاحلا بسح ةددعتم طئاسو " ABSTRACT in this paper we develop a Vhdlbased scalable architecture of a multimedia on demand server model. Te three server subsystems are:the control subsystem, the communication subsystem and the storage subsystem are modeled. The communication subsystem is designed as an interconnection network with meshed-pipe structure and delivers packe...

BACKGROUND Uremia is proposed to increase sympathetic nerve activity (SNA) in hemodialysis patients. The aims of the present study were to determine whether reversal of uremia by successful kidney transplantation (RTX) eliminates the increased SNA and whether signals arising in the diseased kidneys contribute to the increased SNA in renal failure. METHODS AND RESULTS We compared muscle sympat...

BACKGROUND Rituximab (RTX) can be used as a rescue therapy for steroid-dependent nephrotic syndrome (SDNS). However, the efficacy and safety of long-term, repeated use of RTX are not established. This study was conducted to assess the efficacy and safety of long-term, repeated RTX treatment in children. METHODS Eighteen consecutive child patients with SDNS who were treated with three or more ...

INTRODUCTION Rituximab (RTX) therapy of rheumatoid arthritis (RA) exhibits enhanced effectiveness in seropositive patients. Using patient sera, we tested if this improved efficacy was associated with enhanced RTX mediated complement-dependent cytotoxicity (RTX-CDC). METHODS We developed an in vitro assay for RTX-CDC using patient sera and the Daudi human B cell line. Using propidium iodide up...