OBJECTIVE Effects of preoperative steroids on morbidity and mortality after transsternal thymectomy are analyzed. METHODS There were 620 transsternal thymectomies for myasthenia gravis performed in the period 1973-2002. There were 547 patients with nonthymomatous myasthenia, including 17 patients submitted to repeated thymectomy (rethymectomy) and 46 patients with thymoma. There were 522 uppe...

Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells. We show that the overlapping orthologous mouse and human genes are the most accurate candidate cardiogenic genes as these genes identified the most conserved developmental pathways that characterize the cardi...

OBJECTIVE MQX-503 is a novel nitroglycerine preparation designed to absorb quickly and allow local vasodilatation in the skin. We examined the efficacy and tolerability of this medication in Raynaud phenomenon (RP) in a laboratory-based study. METHODS In this multi-centre, double-blind, randomised, placebo-controlled, cross-over study, subjects were treated with 0.5% or 1.25% nitroglycerine o...

چکیدههدف: پژوهش حاضر سهم ذهن آگاهی را بر بهزیستیروانشناختی مورد بررسی قرار داده است. براساس نظر کابات زین1990 ) ذهن آگاهی کیفیتی از هشیاری و به معنای توجه به لحظه )کنونی، توجهی هدفمند و بدون قضاوت میباشد. ذهن آگاهی بابسیاری از مؤلفههای سلامت روان و بهزیستی روانی و کاهشاحساس درد خصوصاً در موارد بیماریهای جسمانی همراه است.روش: ابزارهای استفاده شده در این پژوهش عبارت بودند ازپرسشنامه بهزیستی روانشن...

Protoporphyrinogen oxidase (Protox) inhibitors and other com pounds which block o r stim­ ulate the porphyrin pathway can cause sufficient levels o f porphyrins to accum ulate in plant tissues for severe photodynam ic dam age to occur. The gross sym ptom ology for all o f these p o r­ phyrinogenic herbicides is similar. Porphyrin accum ulation induced by three porphyrinogenic herbicides acifluo...

Objective: The objective of this study was to determine under the view literature, the indications, findings, and complications of diagnostic and operative laparoscopy performed at a teaching hospital. Methods: A total of 503 cases for which the laparoscopy was performed for diagnostic and operative purposes was included into this study. Demographic characteristics, length of operative time, le...

BACKGROUND Our aim was to determine whether regional left ventricular (LV) function on a resting transthoracic echo (TTE) provides prognostic information in patients with varying degrees of ischemia on myocardial perfusion imaging. METHODS Between 2004 - 2009, we identified 503 patients (mean age 69 (SD 11); 79% male) with reversible ischemia on a myocardial SPECT scan who had a TTE within 30...

Understanding the mechanisms of early cardiac fate determination may lead to better approaches in promoting heart regeneration. We used a mesoderm posterior 1 (Mesp1)-Cre/Rosa26-EYFP reporter system to identify microRNAs (miRNAs) enriched in early cardiac progenitor cells. Most of these miRNA genes bear MESP1-binding sites and active histone signatures. In a calcium transient-based screening as...

هدف: پژوهش حاضر به منظور بررسی مقایسه اثربخشی مداخلةشناختی – رفتاری مبتنی بر الگوی مارلات با اثربخشی مداخلة شناختدرمانی مبتنی بر ذهن آگاهی در سلامت روان درمانجویان وابسته بهکراک بود.روش: در یک پژوهش آزمایشی 45 نفر از درمانجویان تحت پوششمرکز ترک اعتیاد جمعیت آفتاب که دوران پس از سمزدایی را می-گذراندند با اجرای مصاحبه و با در نظر گرفتن ملاکهای شمول انتخابشدند. سپس این تعداد به صورت تصادفی در سه گ...