An outbreak of dermatitis in a car assembly factory is described; it affected 5o workers who handled rubber weatherstrips coated with an adhesive. The adhesive was found to contain para-tertiary butyl phenol (P.T.B.P.) formaldehyde resin. Of those patch tested 70% gave positive reactions to the adhesive and 65% to the resin. Improved methods of handling and personal protection succeeded in arre...

Yucatan hairless micropig (YHMP) skin has been shown to have histology and physiologic properties similar to human skin. To assess the relationship between the permeability of corticosteroid ointments and five types of commonly used admixtures of corticosteroid through hairless mice (HM) or YHMP skin and the clinical effects in humans, we conduct by in vitro experiments using HM and YHMP skin. ...

In the delta of southeastern Arkansas, at the National Center for Toxicological Research in Jefferson, two large laboratory rooms are bright with sunlight-not the kind that streams in through windows, but simulated solar energy from tiny lamps using an electromagnetic radiation source that closely mimics the spectrum of sunlight. There, in the heart of the new Phototoxicology Research and Testi...

The purpose of this study was designed to investigate the in vitro and in vivo skin absorption of capsaicin and nonivamide from hydrogels. Various commercialized creams of capsaicin were also compared with hydrogels. Both skin stripping technique and Mexameter were applied to evaluate the level of capsaicin and nonivamide retained in stratum corneum (SC) and skin erythema in vivo. The partition...

Generally white color of the skin is regarded as a feature superiority and prettiness around world. Both males females in Pakistan apply skin-lightening creams (SLC) but they do not know about side-effects their constituents. Skin-lightening products include SLC related ointments. The are made by mixing fates water standard procedure. Here, 20 specimens were obtained subjected to mercury, hydro...