نتایج جستجو برای: ژن pel

تعداد نتایج: 16856  

Journal: :Blood 2002
Eric Oksenhendler Emmanuelle Boulanger Lionel Galicier Ming-Qing Du Nicolas Dupin Tim C Diss Rifat Hamoudi Marie-Thérèse Daniel Félix Agbalika Chris Boshoff Jean-Pierre Clauvel Peter G Isaacson Véronique Meignin

Multicentric Castleman disease (MCD) is a distinct type of lymphoproliferative disorder associated with inflammatory symptoms and interleukin 6 (IL-6) dysregulation. In the context of human immunodeficiency virus (HIV) infection, MCD is associated with Kaposi sarcoma-associated herpesvirus, also called human herpesvirus type 8 (KSHV/HHV8). Within a prospective cohort study on 60 HIV-infected pa...

Journal: :The Journal of clinical investigation 2017
Utthara Nayar Jouliana Sadek Jonathan Reichel Denise Hernandez-Hopkins Gunkut Akar Peter J Barelli Michelle A Sahai Hufeng Zhou Jennifer Totonchy David Jayabalan Ruben Niesvizky Ilaria Guasparri Duane Hassane Yifang Liu Shizuko Sei Robert H Shoemaker J David Warren Olivier Elemento Kenneth M Kaye Ethel Cesarman

Primary effusion lymphoma (PEL) is a largely incurable malignancy of B cell origin with plasmacytic differentiation. Here, we report the identification of a highly effective inhibitor of PEL. This compound, 6-ethylthioinosine (6-ETI), is a nucleoside analog with toxicity to PEL in vitro and in vivo, but not to other lymphoma cell lines tested. We developed and performed resistome analysis, an u...

2016
Fengqin Li Yongjun Jian Zhiyong Xie Yongbo Liu Quansheng Liu

The purpose of this study is to investigate the flow of viscoelastic fluid through a slit polyelectrolyte-grafted (PE-grafted) nanochannel under applied alternating current (AC) electric field. The PE-grafted nanochannel (also called a soft nanochannel) is represented by a rigid surface coated by a polyelectrolyte layer (PEL) in a brush-like configuration. By solving linearized Poisson–Boltzman...

Journal: :Cancer letters 2010
Kwun Wah Wen Blossom Damania

Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus belonging to the gamma-herpesvirinae subfamily. KSHV has been associated with the development of three neoplastic diseases: Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). In this review, we discuss the three KSHV-associated malignancies, KSHV genome, latent and lyti...

2012
S. N. Lahiri S. Mukhopadhyay

In this paper, we consider the penalized empirical likelihood (PEL) method of Bartolucci (2007) for inference on the population mean which is a modification of the standard empirical likelihood and employs a penalty based on the Mahalanobis-distance. We derive the asymptotic distributions of the PEL ratio statistic when the dimension of the observations increases with the sample size. Finite sa...

2002
Thomas Wedi

Common motion compensated hybrid video coding standards such as H.263, MPEG-1, MPEG-2, MPEG-4 are based on a fractional-pel displacement vector (DV) resolution of 1/2-pel. Recent approaches like MPEG-4 (ACE-profile) and H.26L use higher DV resolutions of 1/4-pel and 1/8-pel. In order to estimate and compensate fractional-pel displacements, the image signal has to be interpolated. Especially for...

Journal: :Journal of virology 2000
A Krithivas D B Young G Liao D Greene S D Hayward

The human herpesvirus 8 (HHV-8) latency-associated nuclear antigen (LANA) is expressed in all latently HHV-8 infected cells and in HHV-8-associated tumors, including primary effusion lymphoma (PEL). To better understand the contribution of LANA to tumorigenesis and to the PEL phenotype, we performed a yeast two-hybrid screen which identified the corepressor protein SAP30 as a LANA binding prote...

2015
Emeline Bouffartigues Joana A. Moscoso Rachel Duchesne Thibaut Rosay Laurène Fito-Boncompte Gwendoline Gicquel Olivier Maillot Magalie Bénard Alexis Bazire Gerald Brenner-Weiss Olivier Lesouhaitier Patrice Lerouge Alain Dufour Nicole Orange Marc G. J. Feuilloley Joerg Overhage Alain Filloux Sylvie Chevalier

OprF is the major outer membrane porin in bacteria belonging to the Pseudomonas genus. In previous studies, we have shown that OprF is required for full virulence expression of the opportunistic pathogen Pseudomonas aeruginosa. Here, we describe molecular insights on the nature of this relationship and report that the absence of OprF leads to increased biofilm formation and production of the Pe...

2015
Saravanan Periasamy Harikrishnan A. S. Nair Kai W. K. Lee Jolene Ong Jie Q. J. Goh Staffan Kjelleberg Scott A. Rice

Pseudomonas aeruginosa PAO1 produces three polysaccharides, alginate, Psl, and Pel that play distinct roles in attachment and biofilm formation for monospecies biofilms. Considerably less is known about their role in the development of mixed species biofilm communities. This study has investigated the roles of alginate, Psl, and Pel during biofilm formation of P. aeruginosa in a defined and exp...

Journal: :Blood 1997
M G Horenstein R G Nador A Chadburn E M Hyjek G Inghirami D M Knowles E Cesarman

Primary effusion (body cavity-based) lymphoma (PEL) is a recently recognized subtype of malignant lymphoma that exhibits distinctive clinical and biological features, most notably its usual infection with the Kaposi's sarcoma-associated herpesvirus (KSHV). The vast majority of cases also contain Epstein-Barr virus (EBV). This dual viral infection is the first example of a consistent dual herpes...

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