نتایج جستجو برای: ژن mmp7

تعداد نتایج: 16108  

2018
Jinhua Wang Wan Li Xiangjin Zheng Xiaocong Pang Guanhua Du

FOXC1 is a vital member of FOX families which play important roles in biological processes including proliferation, differentiation, apoptosis, migration, invasion, metabolism, and longevity. Here we are focusing on roles of FOXC1 and their mechanisms in cancers. FOXC1 promoted progress of many cancers, such as breast cancer (especially basal-like breast cancer), hepatocellular carcinoma, gastr...

2015
Hongmei Li Martina Miteva Kellye C. Kirkbride Ming J. Cheng Christopher E. Nelson Elaine M. Simpson Mukesh K. Gupta Craig L. Duvall Todd D. Giorgio

A dual-targeted siRNA nanocarrier has been synthesized and validated that is selectively activated in environments where there is colocalization of two breast cancer hallmarks, elevated matrix metalloproteinase (MMP) activity and folate receptor overexpression. This siRNA nanocarrier is self-assembled from two polymers containing the same pH-responsive, endosomolytic core-forming block but vary...

2013
Yong-Kyun Kwon Seung-Yeul Lee Hwan-Soo Kang Jung-Suk Sung Chong-Kwan Cho Hwa-Seung Yoo Seungjin Shin Jong-Soon Choi Yeon-Weol Lee Ik-Soon Jang

OBJECTIVES Modified regular ginseng extract (MRGX) has stronger anti-cancer activity-possessing gensenoside profiles. METHODS To investigate changes in gene expression in the MRGX-treated lung cancer cells (A549), we examined genomic data with cDNA microarray results. After completing the gene-ontology-based analysis, we grouped the genes into up-and down-regulated profiles and into ontology-...

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