The objective of this study was to evaluate and compare the effects Twin Block Forsus on Posterior Airway Passage (PAP) pharyngeal wall Thickness (PPWT) in treatment Class II division 1 malocclusion. This a 2-arm parallel, randomized controlled trial. A total 24 malocclusion patients indicated for with functional appliances were equally divided among (3M Unitek Corp, Monrovia, Calif) groups. Sk...

A patient without prostatic carcinoma had a high concentration of prostatic acid phosphatase (PAP; EC 3.1.3.2) in his serum. This PAP was bound to IgG ("macro-PAP"), and IgG autoantibodies against PAP were demonstrated in serum. The patient's IgG prolonged the biological half-life of radiolabeled PAP in rats, suggesting that the formation of IgG-PAP complexes was responsible for decreased PAP c...

In 2010, the Food and Drug Administration approved sipuleucel-T for the treatment of asymptomatic or minimally symptomatic castration-resistant metastatic prostate cancer based on demonstration of an improvement in overall survival in a randomized phase III clinical trial (1), one of three recent positive large controlled vaccine trials in a variety of human cancers that show that specific T ce...

Dyslipidemia increases the risk of coronary heart disease in people with diabetes. Increased consumption foods substantial fiber and antioxidants, such as sorghum, can help diabetes manage their lipid profiles improve insulin sensitivity. The study aimed to evaluate how sorghum flour affected diabetic rats' plasma atherosclerosis index (IAP) score blood profile. A randomized control design was ...

Pulmonary alveolar proteinosis (PAP) is a rare pulmonary syndrome characterized by surfactant accumulation in the alveoli, which results impaired gas exchange. There are three types of PAP: primary, secondary and congenital. Autoimmune PAP, under category primary most common form, caused an impairment granulocyte–macrophage colony-stimulating factor (GM-CSF) signalling, due to presence anti-GM-...

The pathogenesis of acquired pulmonary alveolar proteinosis (PAP), a rare lung disease characterized by excessive surfactant accumulation within the alveolar space, remains obscure. Gene-targeted mice lacking the hematopoietic growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) or the signal-transducing b-common chain of the GM-CSF receptor have impaired surfactant clearance...

Background: Heavy metals have been recognized as harmful environmental pollutant known to produce highly toxic effects on different organs and systems of both humans and animals. The aim of this paper is to evaluate the adsorption potential of chitosan for the removal of Pb(II), Fe(II) and Cu(II) ions from aqueous solutions. Methods: This study was conducted in laboratory scale. In this paper ...

BACKGROUND Phosphatidate phosphatase (PAP) plays diverse roles in lipid metabolism and cell signaling. RESULTS A novel yeast PAP is identified as the actin patch protein encoded by APP1. CONCLUSION APP1 and other known genes (PAH1, DPP1, LPP1) are responsible for all detectable PAP activity in yeast. SIGNIFICANCE Identification of App1p as a PAP enzyme will facilitate the understanding of...