هدف: سرطان از جمله مهمترین بیماری­های قرن حاضر است که افراد بسیاری در سراسر جهان به آن مبتلا می­باشند و ضمن افزایش شیوع این بیماری، هنوز درمان مناسبی برای پیدا نشده است. بین پستان شایع­ترین همچنین علت اصلی مرگ میر ناشی زنان محققان بدنبال یافتن راهکارهای درمانی سرطان، ترکیبات دارویی را علیه سرطان­های مختلف سنتز کرده اثرات آ­نها مورد مطالعه قرار می­دهند. سورافنیب یک مهار کننده­ی اوره مولتی­کیناز ...

Let k ≥ 3 be an integer. We show that if d is a positive integer such that the product of any two distinct elements of the set {k−2, k+2, 4k, d} increased by 4 is a square, then d must be 4k(k2−1).

taxus    is an endangered plant which is the only commercial source of paclitaxel, which is used for treatment of ovary and breast cancer. as production of this valuable drug is a destructive process, other alternatives should be considered for its sustainable production. plant tissue and cell culture is a promising method for production of secondary metabolites. in order to optimize yew callus...

introduction: water is the main carrier of herbicides (hc) that its quality plays an important role in herbicide performance hard water has a high concentration of ca++ and mg++ and reviews have shown that calcium, manganese and zinc are the main factors reducing the effectiveness of weak acid herbicides. weak acid herbicides such as glyphosate, paraquat, clethodim and 2, 4 d are compounds that...

heterocyclic systems are one of the most important classes of organic compounds present in nature or synthesized in laboratory. these compounds posses an array of biological activities and are employed in the treatment of commonly occurring diseases. keeping this in view, some new 2-amino-4,6-diarylpyrimidine from chalcones were synthesized. eight novel 2-amino-4,6-diarylpyrimidine derivatives ...

introduction: multiple sclerosis is a chronic inflammatory disease of central nervous system. the etiology of ms is slightly known, but genetic and environmental factors are reported. vitamin d regulates gene expression and affects target cell functions. the aim of this study was to investigate the expression variation of il-2 and il-4 genes under vitamin d supplementation in patients with mult...