In this study, the performance of a centrifugal pump is investigated by adding polyacrylamide (PAM) polymer over the working fluid which is tap water in this case. PAM is a long chain polymer that leads to reduce the wall shear stress and drag in a turbulent fluid. Three different blade profiles including radial, straight backward and circular backward have been examined. For this purpose, a ce...

PAM (Protein Associated with Myc) is an almost ubiquitously expressed protein that is one of the most potent inhibitors of adenylyl cyclase activity known so far. Here we show that PAM is localized at the endoplasmic reticulum in HeLa cells and that upon serum treatment PAM is recruited to the plasma membrane, causing an inhibition of adenylyl cyclase activity. We purified the serum factor that...

Slow infiltration rates constrain effective and economical irrigation in some sandy loam soils in California. Polyacrylamide (PAM) has increased soil infiltration in some areas, especially in soils high in clay or silt. Field trials near Fresno, CA, with PAM failed to show improved infiltration. Laboratory experiments were conducted to investigate PAM effect on infiltration of various quality w...

ANP (atrial natriuretic peptide) is widely recognized as an important vasorelaxant, diuretic, and cardioprotective hormone. Little is known, however, about how ANP-secretory vesicles form within the atrial myocytes. Secretory vesicles were visualized by fluorescence microscope imaging in live rat atrial myocytes expressing proANP-enhanced green fluorescent protein (EGFP), or N-terminal-mutated ...

Amidated neuropeptides play essential roles throughout the nervous and endocrine systems. Mice lacking peptidylglycine α-amidating monooxygenase (PAM), the only enzyme capable of producing amidated peptides, are not viable. In the amidation reaction, the reactant (glycine-extended peptide) is converted into a reaction intermediate (hydroxyglycine-extended peptide) by the copper-dependent peptid...

During the anaerobic digestion of dewatered sludge, polyacrylamide (PAM), a chemical conditioner, can usually be consumed as a carbon and nitrogen source along with other organic matter (e.g., proteins and carbohydrates in the sludge). However, a significant accumulation of acrylamide monomers (AMs) was observed during the PAM biodegradation process. To improve the anaerobic hydrolysis of PAM, ...

Invasive lobular and ductal breast tumors have distinct histologies and clinical presentation. Other than altered expression of E-cadherin, little is known about the underlying biology that distinguishes the tumor subtypes. We used cDNA microarrays to identify genes differentially expressed between lobular and ductal tumors. Unsupervised clustering of tumors failed to distinguish between the tw...

Rodrick D. Lentz* USDA-ARS Northwest Irrigation and Soils Research Lab. 3793 N 3600 E Kimberly, ID 83341 High water infiltration rates in unlined canals, reservoirs, and the inflow end of furrows relative to outflow ends result in excessive seepage losses and reduced furrow irrigation application uniformity. This study evaluated the use of cross-linked, anionic, polyacrylamide hydrogel (XPAM), ...

Agonists at dopamine D2 and D3 receptors are important therapeutic agents in the treatment of Parkinson's disease. Compared with the use of agonists, allosteric potentiators offer potential advantages such as temporal, regional, and phasic potentiation of natural signaling, and that of receptor subtype selectivity. We report the identification of a stereoselective interaction of a benzothiazol ...

A novel ZIF-8 assisted polyacrylamide functionalized silica polar stationary phase was prepared by a facile method of adding nanoparticles and into (PAM) aqueous solution, then stirring the mixture until solution evaporated absolutely with help mechanical agitator. Interestingly, (PAM-Sil@ZIF-8/PAM) showed favorable hydrophilicity, as demonstrated good separation performance strong retention ab...