PCE (protein continuum electrostatics) is an online service for protein electrostatic computations presently based on the MEAD (macroscopic electrostatics with atomic detail) package initially developed by D. Bashford [(2004) Front Biosci., 9, 1082-1099]. This computer method uses a macroscopic electrostatic model for the calculation of protein electrostatic properties, such as pK(a) values of ...

Oscillatory phase coupling within large-scale brain networks is a topic of increasing interest within systems, cognitive, and theoretical neuroscience. Evidence shows that brain rhythms play a role in controlling neuronal excitability and response modulation (Haider B, McCormick D. Neuron 62: 171-189, 2009) and regulate the efficacy of communication between cortical regions (Fries P. Trends Cog...

This paper investigates the forecasting accuracy of the trimmed mean inflation rate of the Personal Consumption Expenditure (PCE) deflator. Earlier works have examined the forecasting ability of limited-influence estimators (trimmed means and the weighted median) of the Consumer Price Index but none have compared the weighted median and trimmed mean of the PCE. Also addressed is the systematic ...

The pneumococcal phosphorylcholine esterase (Pce or CbpE) is a modular protein that hydrolyses the phosphorylcholine residues present in the teichoic and lipoteichoic acids of the pneumococcal cell wall. Pce has been crystallized using the hanging-drop vapour-diffusion method at 291 K. Diffraction-quality monoclinic crystals belong to space group C2, with unit-cell parameters a = 169.82, b = 57...

Status of This Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Abstract This document presents a set of requirements for a Path Computation Element (PCE) discovery mechanism that would allow a Path Computation Client (PCC) to discover dynamically and automatically a set of PCEs along wi...

A Path Computation Element (PCE) may be required to perform dependent path computations. Dependent path computations are requests that need to be synchronized in order to meet specific objectives. An example of a dependent request would be a PCE computing a set of services that are required to be diverse (disjointed) from each other. When a PCE computes sets of dependent path computation reques...

Prenatal drug exposure, particularly prenatal cocaine exposure (PCE), incurs great public and scientific interest because of its associated neurodevelopmental consequences. However, the neural underpinnings of PCE remain essentially uncharted, and existing studies in school-aged children and adolescents are confounded greatly by postnatal environmental factors. In this study, leveraging a large...

Tuning the band alignment is proved to be an effective way to facilitate carrier transportation and thus enhance the power conversion efficiency (PCE) of solar cells. Doping the compact layer with metal ions or modifying the interfaces among functional layers in perovskite solar cells (PSCs) can appreciably improve the PCE of PSCs. Inspired by the rare earth elemental doping of TiO2, which has ...

The piecewise-constant exponential model is a semi-parametric continuous time duration model.1 The model is semi-parametric in the sense that the shape of the hazard rate with respect to time is not specified a priori but is determined by the data. The basic idea underlying the PCE model is that the duration time can be divided up into discrete units in each of which the hazard rate is assumed ...

BACKGROUND Trichloroethene and tetrachloroethene are the most common pollutants in groundwater and two of the priority pollutants listed by the U.S. Environmental Protection Agency. In previous studies on TCE and PCE photolysis and photochemical degradation, concentration ranges exceeding environmental levels by far with millimolar concentrations of TCE and PCE have been used, and it is not cle...