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In continuation of our study of the metabolism of L-lysine, ar-aminoadipic acid, which is formed from lysine in guinea pig liver homogenate (1)) was synthesized with Cl4 in the e-position. The metabolism of the latter compound was followed by search for the radioactive tracer among the probable metabolic products. Two have been identified, a-ketoadipic and glutaric acids. The accompanying diagr...

Please check this proof carefully. Our staff will not read it in detail after you have returned it. Translation errors between word-processor files and typesetting systems can occur so the whole proof needs to be read. Please pay particular attention to: tabulated material; equations; numerical data; figures and graphics; and references. If you have not already indicated the corresponding autho...

Translation errors between word-processor files and typesetting systems can occur so the whole proof needs to be read. Please pay particular attention to: tabulated material; equations; numerical data; figures and graphics; and references. If you have not already indicated the corresponding author(s) please mark their name(s) with an asterisk. Please e-mail a list of corrections or the PDF with...

Clinical practice guidelines (CPGs)* (throughout the text, terms marked with an asterisk are defined in Table 1 in alphabetical order) [1] have become important tools in shaping the care of individuals with chronic kidney disease (CKD). CPGs inform patient care, scientific debate, research agendas and policies. At the same time, CPGs have been criticized for restricting the care provided by phy...

1. Main theorem. Let x = (xo, xi, • • • ) be a sequence of complex numbers and let | x \ he the norm | x | = (^Z | x„ |2)1/2 2:0. Let an asterisk denote complex conjugation. If \x\ < <» and |y| < oo, let [x, y] = [y, x] denote the sum of the series ^T,xnyn, that is, the "scalar" product of y by x*. For a given x with a finite norm |x|, let x(t) denote a function of class i2(0, 27r) having the F...

said to have an allele labeled as *2, shown on the test report as CYP2C19*2. No one in the doctor’s office— including the doctor himself—knew the significance of the asterisk. “The doctor called me and said, ‘I got this interesting value. It was CYP2C19 squared,’” Laposata says. “And I said, ‘What do you mean, squared?’ The doctor thought it was a superscript and *2 meant it was squared. I said...

This paper studies the analysis of reductio ad absurdum by Ibn Sı̄nā (known to the Latin West as Avicenna), who was born in 980 in a village near the Bactrian town of Balkh on the Silk Road, and died in 1037 after a career spent moving around within the present boundaries of Iran. References to Ibn Sı̄nā’s writings are to his Arabic texts listed in the bibliography, and are given in the format pa...