Luteinizing hormone (LH) has been shown to be the only hormone essential for maintenance of testicular testosterone pr0duction.l LH mediates its effect on testicular steroidogenesis by binding to high affinity receptors in the plasma membrane of Leydig cells. In recent years, numerous investigators have reported that in vivo administration of LH or human chorionic gonadotropin (hCG) results in ...

We investigated the possible clinical correlates between the serum LH concentration and characteristics of frailty and determined the presence and concentration of a genetic LH variant in an independently living population of elderly men. After exclusion of subjects with severe mobility problems and signs of dementia, 403 healthy men (aged 73-94 yr) were randomly selected from a population-base...

A sensitive and specific double antibody radioimmunoassay has been developed capable of measuring LH-RH in extracted human plasma. Thyrotropin releasing hormone, lysine vasopressin and most of LH-RH analogues did not appear to affect the assay. Hypothalamic extract and some of the LH-RH analogues produced displacement curves which were parallel to that obtained with the synthetic LH-RH. Sensiti...

The present study was designed to achieve the production and characterization of polyclonal antibody of luteinizing hormone (AntiLH) as a basic component of LH radioimmunoassay (RIA). The main objective was to improve the immunogenicity of LH by conjugation of LH with bovine serum albumin (LH: BSA) as a protein carrier using Ethyl dimethylaminopropyl Carbodiimide (ECDI). Production of Anti-LH w...

The “learned helplessness” (LH) model in rats is widely used a battery of tests to assess depression-like behaviour and the effects antidepressants. considered be suffi ciently valid, though having some limitations with reproducibility. This review discusses possibilities using for assessing symptoms depressive-like state pathogenesis depression, as well factors affecting reproducibility LH are...