نتایج جستجو برای: پروتئومیکس مقایسهای itraq

تعداد نتایج: 1763  

Journal: :Journal of the American Society for Mass Spectrometry 2008

2017
Jianfang Huang Weiwei You Xuan Luo Caihuan Ke

The abalone Haliotis discus hannai is an important aquaculture species that is grown for human consumption. However, little is known of the genetic mechanisms governing muscle growth in this species, particularly with respect to proteomics. The isobaric tag for relative and absolute quantitation (iTRAQ) method allows for sensitive and accurate protein quantification. Our study was the first to ...

2017
Xiufang Bi Yongtao Wang Xiaosong Hu Xiaojun Liao

High pressure carbon dioxide (HPCD) could cause sublethally injured cells (SICs), which may cause food poisoning and spoilage during food storage and limit its application. Therefore, the formation of SICs of Escherichia coli O157:H7 was investigated by isobaric tag for relative and absolute quantification (iTRAQ) proteomic methods in this study for better controlling the SICs induced by HPCD. ...

2014
Bo Xu Zhixiong Cai Yongyi Zeng Lihong Chen Xiaobo Du Aimin Huang Xiaolong Liu Jingfeng Liu

AIMS Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and it is still lacking effective prognostic biomarkers so far. Previous results of the iTRAQ-based quantitative proteomics study (iTRAQ-2DLC-MS/MS) have shown that α-methylacyl-CoA racemase (AMACR) might be a promising prognostic biomarker for the early recurrence/metastasis of hepatocellular carcinoma (HCC)....

2011
Ville Parviainen Sakari Joenväärä Eija Tukiainen Minna Ilmakunnas Helena Isoniemi Risto Renkonen

Plasma proteome is widely used in studying changes occurring in human body during disease or other disturbances. Immunological methods are commonly used in such studies. In recent years, mass spectrometry has gained popularity in high-throughput analysis of plasma proteins. In this study, we tested whether mass spectrometry and iTRAQ-based protein quantification might be used in proteomic analy...

2015
Xiaofei Li Qi Wang Yanni Gao Xiaole Qi Yongqiang Wang Honglei Gao Yulong Gao Xiaomei Wang

Avian leukosis virus subgroup J (ALV-J) is an avian oncogenic retrovirus that can induce various clinical tumors and has caused severe economic losses in China. To improve our understanding of the host cellular responses to virus infection and the pathogenesis of ALV-J infection, we applied isobaric tags for relative and absolute quantification (iTRAQ) labeling coupled with multidimensional liq...

Journal: :Journal of proteome research 2017
Steven C Hall Maria E Hassis Katherine E Williams Matthew E Albertolle Akraporn Prakobphol Andrew B Dykstra Megan Laurance Katherine Ona Richard K Niles Namrata Prasad Matthew Gormley Caroline Shiboski Lindsey A Criswell H Ewa Witkowska Susan J Fisher

We used isobaric mass tagging (iTRAQ) and lectin affinity capture mass spectrometry (MS)-based workflows for global analyses of parotid saliva (PS) and whole saliva (WS) samples obtained from patients diagnosed with primary Sjögren's Syndrome (pSS) who were enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA) as compared with two control groups. The iTRAQ analyses rev...

2013
Valeria Severino Livia Malorni Anna Emilia Cicatiello Vittoria D’Esposito Salvatore Longobardi Nicola Colacurci Nadia Miraglia Nicola Sannolo Annarita Farina Angela Chambery

The emergence of high-throughput protein quantification methodologies has enabled the comprehensive characterization by longitudinal and cross-sectional studies of biological fluids under physiological and pathological conditions. In particular, the simultaneous investigation of cytokines and growth factors signaling pathways and their associated downstream effectors by integrated multiplexed a...

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