We showed previously that the orphan nuclear receptor Tlx is required for the correct establishment of the pallio-subpallial boundary. Loss of Tlx results in a dorsal expansion of ventral markers (e.g., the homeodomain protein GSH2) into the ventralmost pallial region, i.e., the ventral pallium. We also observed a disproportionate reduction in the size of the Tlx mutant lateral ganglionic emine...

Although the development of the vertebrate eye is well described, the number of transcription factors known to be key to this process is still limited. The localized expression of the orphan nuclear receptor Tlx in the optic cup and discrete parts of the central nervous system suggested the possible role of Tlx in the formation or function of these structures. Analyses of Tlx targeted mice reve...

Conventional vascular intervention (VI) procedures are typically performed manually under exposure to X-rays, whereby several problems presented that need be addressed owing the patients and doctors being exposed large amounts of radiation. In such cases, employing radiation protection units is not a long-term solution avoid physical damage. Therefore, overcome these issues, we propose robotic ...

Perum Jasa Tirta II is a State-Owned Enterprise (BUMN) in the form of Public Company engaged providing raw water and electricity for public benefit this II, there are various units. One them Jatiluhur Tourism AMDK Business Unit, which produces types demineralized drinking water, namely gallons, 600 ml bottles, 330 240 cups. The implementation 3 shifts to meet production targets activities carri...

Neural stem cells (NSCs) continually generate functional neurons in the adult brain. Due to their ability to proliferate, deregulated NSCs or their progenitors have been proposed as the cells of origin for a number of primary central nervous system neoplasms, including infiltrating gliomas. The orphan nuclear receptor TLX is required for proliferation of adult NSCs, and its upregulation promote...

Subjective workload and situation awareness measures, such as the NASA task load index (TLX) situational rating technique (SART), are frequently used in human–system evaluation. However, interpretation of these ratings is debated. In this study, empirical evidence for measures' theoretical assumptions was investigated by comparing operators' collected immediately after performing a scenario acq...