The new Mannich base VEP (N,N’-bis-(5,5’-diethyl-barbituryl-1-methyl)-piperazine), has been synthetized by condensation of veronal with formaldehyde and piperazine following a Mannich procedure. The new binuclear complex Cu2VEP(X)4·4H2O , X=ClO4where VEP stands for N,N’-bis-(5,5’-diethyl-barbituryl-1-methyl)-piperazine, were obtained by metal ligand direct synthesis. Tetrahedral geometry of the...

The clinical and visual evoked potential (VEP) findings were analysed in 18 patients with anterior ischaemic optic neuropathy. The VEP studies showed a variety of abnormalities which could be interpreted as being the result of subcomponent interaction consequent upon loss or attenuation of the normal macular-derived P100 component. Delay of normal VEP subcomponents was not seen. The VEP finding...

One week of solitary confinement of prison inmates produced significant changes in their EEG frequency and visual evoked potentials (VEP) that parallel those reported in laboratory studies of sensory deprivation. EEG frequency declined in a nonlinear manner over the period. VEP latency, which decreased with continued solitary confinement, was shorter for these 5s than for control 5s whose VEP l...

OBJECTIVES Visual evoked potentials (VEPs) show abnormal responses in newly-diagnosed insulin-dependent diabetic (IDDM) patients. Electrophysiological methods allow one to dissect and explore different structures contributing to neural conduction in the visual pathways. The aim of our work was to assess whether the VEP abnormalities are due to impaired function of the retinal layers and/or a de...

OBJECTIVE To compare the visual evoked potentials (VEP) in patients with acute optic neuritis, recurrent optic neuritis, and optic neuritis with multiple sclerosis. MATERIAL AND METHOD The authors retrospectively reviewed VEP latency records of the patients with optic neuritis in Siriraj Hospital from 1995 to 2005 and divided them into three groups, acute optic neuritis, recurrent optic neuri...

While evoked potentials are sensitive tools for diagnosing multiple sclerosis, little is known about their prognostic value and their role in determining the course of the disease. To validate the visual and motor evoked potentials (VEP and MEP) as measures for the course of multiple sclerosis, we examined prospectively 30 patients with relapsing-remitting or secondary progressive multiple scle...

Visual evoked potentials (VEP) are of particular importance for the objectivization of organic and functional defects in the visual system. This study presents, for the first time, the use of systematic VEP-monitoring in connection with manual acupuncture and laserpuncture in 40 healthy volunteers. We were not able to find significant changes in latency or in the amplitudes of VEP ́s during acup...

PRIMARY OBJECTIVE The purpose of this study was to assess the effect of check size (CS) and contrast (C) on VEP amplitude and latency in visually-normal (VN) and in mild traumatic brain injury (mTBI) adults to develop an optimized test protocol in each group. RESEARCH DESIGN AND METHODS Subjects were comprised of VN (n = 19) and individuals with mTBI (n = 16). Full-field, pattern VEP testing ...

OBJECTIVE To determine the comparison of its clinical utility and safety profile for visual evoked potential (VEP) monitoring during prone spine surgeries under total intravenous anesthesia (TIVA) versus balanced general anesthesia using the SightSaver™ visual stimulator. METHODS The protocol was designed asa pilot, single center, prospective, randomized, and double-arm study. Subjects were r...