background: infection with parvovirus b19 may cause fetal losses including spontaneous abortion, intrauterine fetal death and non-immune hydropsfetalis. the aim of this study is to determine the frequency of parvovirus b19 in formalin fixed placental tissues in lost fetuses using real-time pcr method.   methods : in this cross-sectional study, 100 formalin fixed placental tissues with unknown c...

INTRODUCTION The frequency of fetopathogenic viruses and Toxoplasma gondii infections in the TORCH group (Toxoplasma gondii, rubella virus, cytomegalovirus (CMV), herpes simplex virus) together with Parvovirus B19 (B19) in pregnant women with bad obstetric history (BOH) and/or concurrent pregnancy complications was investigated. METHODOLOGY Sixty women (20-35 years) with BOH and/or antecedent...

Human parvovirus B19 is considered an etiologic agent of aplastic anemia in immunosuppressed patients. Microscopic vasculitis, with or without renal involvement, has recently been attributed to this viral infection in immunocompetent patients. This study describes four cases of thrombotic renal graft microangiopathy presumably secondary to B19 infection. Twelve to 50 days after transplantation,...

OBJECTIVE We aimed to investigate posttransplant Epstein-Barr virus (EBV) and parvovirus B19 DNA in allogeneic stem cell transplant patients between 2009 and 2010. MATERIALS AND METHODS Forty-five adult patients in whom allogeneic stem cell transplantation was performed between April 2009 and November 2010 in the Erciyes University Faculty of Medicine, Department of Internal Medicine, Divisio...

BACKGROUND Human parvovirus B19 is the etiologic agent of erythema infectiosum in children. It is also associated with other clinical manifestations in different target groups. Patients with chronic hemolytic anemia are at high risk of developing acute erythroblastopenia following infection by the virus. They usually become highly viremic and pose an increased risk of virus transmission. Close ...

We describe a case of asymptomatic human parvovirus B19 infection during pregnancy that led to hydrops fetalis and foetal death. The diagnosis was confirmed by the presence of parvovirus B19-specific IgM antibodies in the maternal serum and the pathognomonic findings, which showed intranuclear eosinophilic viral inclusions and margination of chromatin in foetal cells of haemopoietic lineage. De...

BACKGROUND Human parvovirus B19 (B19) is a ubiquitous and clinically significant pathogen, causing erythema infectiosum, arthropathy, transient aplastic crisis, and intrauterine fetal death. The phenotype of CD8+ T cells in acute B19 infection has not been studied previously. METHODS AND FINDINGS The number and phenotype of B19-specific CD8+ T cell responses during and after acute adult infec...

B19 virus is a human virus belonging to the genus Erythrovirus: The genetic diversity among B19 virus isolates has been reported to be very low, with less than 2% nucleotide divergence in the whole genome sequence. We have previously reported the isolation of a human erythrovirus isolate, termed V9, whose sequence was markedly distinct (>11% nucleotide divergence) from that of B19 virus. To dat...

BACKGROUND AND OBJECTIVES Trans-placental transmission of parvovirus B19 during pregnancy can causes adverse outcomes. Regarding its importance in prenatal care, we decided to study prevalence of parvovirus B19 infection among pregnant woman in Ardabil, Iran. MATERIALS AND METHODS In a community based study with a cluster sampling, 350 pregnant women that attended in health care centers in Ar...