BACKGROUND Extracellular phospholipase, proteinase, and coagulase are accounted as the major virulence factors in Candida albicans. Several reports showed that the incidence of resistance to fluconazole has risen during last two decades. OBJECTIVES The present study has investigated the extracellular enzymes of C. albicans and non-albicans species isolated from both patients with vaginitis an...

OBJECTIVE During pregnancy cytokines and inflammatory mediators stimulate the expression of prostaglandin, the levels of which determine the onset of labor. The aim of this work was to study interleukin IL-1beta, IL-6 and IL-8 levels in the vaginal discharge, serum and urine of pregnant women with genitourinary infection before and after specific treatment. One hundred and fifty-one patients we...

was regular and symptomless. There were no other symptoms. Both the mother and the patient were much upset by the condition, as the girl was to be married within a few months. Previous history.?The patient had always maintained good health. She gave no history of dysentery. Physical examination.?The patient was a well-built girl. General examination was negative. The patient was unusually shy a...

For more than 10 years very satisfactory results have been obtained in the treatment of trichomonal vaginitis using the standard 7-day course of metronidazole 200 mg. three times a day (Rodin, King, Nicol, and Barrow, 1960). In a recent trial it was shown that a 5-day course of 400 mg. twice daily produced equally satisfactory results, and was probably an easier regime from the patient's point ...

The patients were seen at the V.D. Clinic of the Central Middlesex Hospital. Prostitutes and women known to be very promiscuous were excluded from the trial as it was thought that the re-infection rate might make the interpretation of results difficult. Flagyl (200 mg. three times daily for 10 days) and dummy tablets were dispensed in identical packets which were randomized and numbered. The ke...

The reproductive tract infection (RTI) or genital tract infection (GTI) is a global health problem which affects men, women, families and communities. These infections threat the women’s health and may have severe consequences such as infertility, ectopic pregnancy, chronic pelvic pain, abortion and an increased risk of HIV transmission. Therefore, proper prevention and treatment of these disea...