The data described are related to the article entitled "Sequence Analysis of Meq oncogene among Indian isolates of Marek׳s Disease Herpesvirus" M. Gupta, D. Deka, Ramneek, 2016. Seven meq genes of Ludhiana Marek׳s disease virus (MDV) field isolates were PCR amplified by using proof reading Platinum Pfx DNA polymerase enzyme, sequenced and then analyzed for the distinct polymorphisms and point m...

PURPOSE To investigate the relationship between lactate dehydrogenase A (LDH-A) expression, lactate concentration, cell metabolism, and metastases in murine 4T1 breast tumors. EXPERIMENTAL DESIGN Inhibition of LDH-A expression and protein levels were achieved in a metastatic breast cancer cell line (4T1) using short hairpin RNA (shRNA) technology. The relationship between tumor LDH-A protein ...

Preparations of pooled Friend virus used in this laboratory were found to contain lactate dehydrogenase (LDH) virus. Interrelationships between these viruses and the effects of drug treatment i~ vivo and virus neutralization in vitro were studied. Both 6-mercaptopurine and streptonigrin administered to Friend virus-infected mice delayed the onset of the 10to 100-fold normal elev,%tion of plasma...

The procedure used to determine the infective titer of the LDH agent, the reproducibility of this assay, and the relationship between virus dose and plasma enzyme activity were described. Multiplication of the LDH agent began within 6 hours after infection and reached 10(10.8) ID(50)/ml of plasma within 24 hours. The titer rapidly decreased over the next 72 hours but viremia persisted for at le...

Induction of lactic dehydrogenase (LDH) antibody with porcine LDH in L1210 leukemia-bearing DBA/2 mice can induce remissions of the disease. The concurrent, limited use of a cytotoxic agent (azathioprine) in combination with LDH has been investigated and found to be advantageous in terms of obtaining a greater number of prolonged remis sions (over 150 days) than does the use of LDH alone. The p...

BACKGROUND Serum lactate dehydrogenase (LDH) is elevated in various diseases. OBJECTIVES To analyze serum LDH as a distinguishing clinical biomarker and as a predictor of in-hospital outcome in admitted medical patients. METHODS We analyzed a cohort of all 158 patients with very high isolated LDH (LDH > or = 800 IU/ml without concomitant elevations of alanine aminotransferase and aspartate ...

Induction of lactic dehydrogenase (LDH) antibody with porcine LDH in L1210 leukemia-bearing DBA/2 mice can induce remissions of the disease. The concurrent, limited use of a cytotoxic agent (azathioprine) in combination with LDH has been investigated and found to be advantageous in terms of obtaining a greater number of prolonged remis sions (over 150 days) than does the use of LDH alone. The p...

By YALE RABINOWITL AND ALBERT A. D rz With the technical assistance of Tina Lubrano, Inge Schimo and Betty A. Wilhite II ESULTS OF A STUDY OF CHANGES in lactic dehydrogenase (LDH) occurring in cultures of normal human lymphocytes were reported recently.’ It was shown that lymphocytes in cultures without phytohemagglutinin (PHA) showed little change in total LDH activity or in isozyme patterns; ...

BACKGROUND The aims of this study were to analyze the prognostic value of baseline lactate dehydrogenase (LDH) among nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiation therapy (IMRT), and to evaluate the potential application of LDH in monitoring treatment efficacy dynamically. MATERIAL AND METHODS From June 2005 to December 2010, 1188 patients with non-metastati...