BACKGROUND AND PURPOSE Although intravenous (IV) thrombolysis is the standard treatment for patients with ischemic stroke occurring within 3 hours from symptom onset, a few interventional neuroradiologists have been treating this category of patients by an intra-arterial (IA) route for >25 years. However, evidence is still required to support the clinical feeling that IA treatment, which needs ...

The genetic and biochemical basis for the inclusion of T cell alloreactivity within the immunological repertoire of T helper (Tn) 1 lymphocytes remains a perplexing problem (1, 2). Recent evidence (3-9) suggests that the ability of Tn cells to bind to molecular complexes formed on antigen-presenting ceils between a nominal antigen and either self or nonself (allo) Ia molecules regulates their d...

The mechanism of induction of murine macrophage Ia expression by lipopolysaccharide (LPS) was studied. Intraperitoneal injection of 1 microgram of LPS resulted in a 3- to 10-fold increase in the number of IA-positive peritoneal macrophages (flow cytometry and immunofluorescence and a 6-to 16-fold increase by radioimmunoassay. The isolated lipid A moiety of LPS was a potent inducer of macrophage...

OBJECTIVE To predict ambulatory capacity, 1 month after physical therapy following hip fracture surgery. METHODS A retrospective chart review was carried out. Patients more than 60 years old, who underwent hip fracture surgery and received physical therapies, were selected (n=548). Age, gender, presence of cognitive dysfunction, combined medical diseases, combined fractures, previous history ...

We have performed Monte Carlo simulations of type Ia supernova (SN Ia) surveys to determine their efficiency in discovering peculiar overluminous and underluminous SNe Ia. We determined how the type of survey (magnitudelimited, distance-limited, or a hybrid) and its characteristics (observations frequency, detection limit, and host limit) affect the discovery of peculiar SNe Ia. We find that th...

The nature of Ia antigens which appear on human T cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the Ia antigen framework. T cells were purified using monoclonal antibodies directed either at the entire T-cell population (OKT3) or the T-cell inducer subset (OKT4). By indirect immunofluorescence, it was shown that t...

The presence of Ia-like antigens was demonstrated on a small population (2-6%) of highly purified human circulating T lymphocytes by immunofluorescence with a rabbit anti-Ia serum raised against the isolated bimolecular Ia structure. The Ia+ T lymphocytes have no surface or intracellular immunoglobulins. The expansion of this Ia+ T-cell population was encountered in certain patients. Ia antigen...

As a foundation for the IA, six topical reports were written by teams of experts. Public comments on the six reports were received from 34 organizations and individuals. Those reports and the public comments received on them, were used to draft the IA. The draft of the IA was also made available for public comment and those comments considered in completing the IA. Public comments on the draft ...

The IA-64 architecture is designed with a unique combination of rich features so that it overcomes the limitations of traditional architectures and provides performance scalability for the future. The IA-64 features expose new opportunities for the compiler to optimize applications. We have incorporated into the Intel IA-64 compiler the key technology necessary to exploit these new optimization...