In large scale data centers, controlling tail latencies of IO requests keeps storage performance bounded and predictable, which is critical for infrastructure resource planning. This work provides a transparent mechanism for applications to pass prioritized IO commands to storage devices. As a consequence, we observe much shorter tail latencies for prioritized IO while impacting nonprioritized ...

BACKGROUND The fraction of inspired oxygen (F(IO(2))) is quoted for different oxygen delivery systems, but variations in inspiratory flow and tidal volume make precise measurement difficult. We developed a reliable method of measuring the effective F(IO(2)) in patients receiving supplemental oxygen. METHODS Ten subjects with chronic hypoxemia breathed through a mouthpiece with a sampling prob...

AIM To evaluate the diagnostic accuracy of IO-SE in comparison to IO-CEUS for the differentiation between malignant and benign liver lesions. MATERIAL AND METHODS In a retrospective diagnostic study IO-CEUS and SE examinations of 49 liver lesions were evaluated and compared to histopathological examinations. Ultrasound was performed using a multifrequency linear probe (6-9 MHz). The loops of ...

A library for parallel IO and data management has been developed for large-scale multi-physics simulations. The goal of the library is to provide sustainable, interoperable, efficient, scalable, and convenient tools for parallel IO and data management for high-level data structures in applications, and to provide tools for the connection between applications. The high-level data structures incl...

Indistinguishability obfuscation (iO) has emerged as a surprisingly powerful notion. Almost all known cryptographic primitives can be constructed from general purpose iO and other minimalistic assumptions such as one-way functions. A major challenge in this direction of research is to develop novel techniques for using iO since iO by itself offers virtually no protection for secret information ...

BACKGROUND Point-of-care (POC) testing is highly useful when treating critically ill patients. In case of difficult vascular access, the intraosseous (IO) route is commonly used, and blood is aspirated to confirm the correct position of the IO-needle. Thus, IO blood samples could be easily accessed for POC analyses in emergency situations. The aim of this study was to determine whether IO value...

BACKGROUND Surgery of the inferior oblique muscle (IO) has undergone significant changes in the past 160 years. Many investigators have contributed to our understanding of the action of this muscle and to the surgical options that have developed. This article reviews the history of IO surgery with particular emphasis on the anterior transposition procedure. METHODS Anatomic and physiologic st...

Liquid biopsy (LB) is a feasible tool able to detect genomic alterations in cancer at baseline and also as longitudinal monitoring identify resistance mutations. In patients (pts) with mNSCLC, when tissue remains difficult procedure, LB might be crucial for therapeutical options, especially the immunotherapy (IO) target therapy era. The aim of this bicentric study assess prognostic value mNSCLC...

Integrated optics (IO) is an optical technology that allows to reproduce optical circuits on a planar substrate. Since 1996, we have investigated the potentiality of IO in the framework of astronomical single mode interferometry. We review in this paper the principles of IO, the requirements for interferometry and the corresponding solutions offered by IO, the results of component characterizat...