نتایج جستجو برای: موتاسیون hfe

تعداد نتایج: 2354  

2014
Taylor Daniels Daniel Smith-Tone

Multivariate Public Key Cryptography (MPKC) has been put forth as a possible post-quantum family of cryptographic schemes. These schemes lack provable security in the reduction theoretic sense, and so their security against yet undiscovered attacks remains uncertain. The effectiveness of differential attacks on various field-based systems has prompted the investigation of differential propertie...

2007
Vivien Dubois Louis Granboulan Jacques Stern

Multivariate Cryptography has been an active line of research for almost twenty years. While most multivariate cryptosystems have been under attack, variations of the basic schemes came up as potential repairs. In this paper, we study the Internal Perturbation variation of HFE recently proposed by Ding and Schmidt. Although several results indicate that HFE is vulnerable against algebraic attac...

Journal: :Pediatrics 2001
K F Murray K V Kowdley

Journal: :The American journal of medicine 2002
Jill Waalen Vincent Felitti Terri Gelbart Ngoc J Ho Ernest Beutler

PURPOSE Mutations of the HFE gene that cause hereditary hemochromatosis may be associated with an increased risk of cardiovascular disease. We examined the relation between two HFE mutations (C282Y and H63D), indicators of iron homeostasis, and the prevalence of coronary heart disease in a large population of white adults. SUBJECTS AND METHODS We conducted a cross-sectional study of 30,916 wh...

Journal: :Annals of internal medicine 2000
H B El-Serag J M Inadomi K V Kowdley

BACKGROUND Screening for hereditary hemochromatosis is traditionally done by using serum iron studies. However, mutation analysis of the hemochromatosis-associated HFE gene has recently become available. OBJECTIVE To compare the cost-effectiveness of no screening with four screening strategies that incorporate HFE gene testing or serum iron studies. DESIGN Cost-effectiveness analysis. DAT...

2017
Qi Liu

Hesitant fuzzy set (HFS), which can be accurately and perfectly described in terms of the opinions of decision makers, is considered as a powerful tool to express uncertain information in the process of multi-attribute decision making (MADM) problems. The core of the HFS is the hesitant fuzzy element (HFE).This paper developed a method, which using the interval probabilistic hesitant fuzzy elem...

Journal: :Blood 2003
Robert J Simpson Edward S Debnam Abas H Laftah Nita Solanky Nick Beaumont Seiamak Bahram Klaus Schümann S Kaila S Srai

Hereditary hemochromatosis is a common iron-loading disorder found in populations of European descent. It has been proposed that mutations causing loss of function of HFE gene result in reduced iron incorporation into immature duodenal crypt cells. These cells then overexpress genes for iron absorption, leading to inappropriate cellular iron balance, a persistent iron deficiency of the duodenal...

2014
Jean-François Truchon B. Montgomery Pettitt Paul Labute

We show that an Ng bridge function modified version of the three-dimensional reference interaction site model (3D-RISM-NgB) solvation free energy method can accurately predict the hydration free energy (HFE) of a set of 504 organic molecules. To achieve this, a single unique constant parameter was adjusted to the computed HFE of single atom Lennard-Jones solutes. It is shown that 3D-RISM is rel...

2013
Pascale Carayon Sarah Kianfar

Many patient safety incidents are related to lack of attention to human factors and ergonomics (HFE) in the design and implementation of technologies, processes, workflows, jobs, teams and sociotechnical systems. For instance, a systems analysis of medication errors 1 identified a range of proximal causes of medication errors, such as rule violations, memory slips and lapses, poor communication...

Journal: :The Journal of biological chemistry 1999
C N Roy D M Penny J N Feder C A Enns

HFE is the protein product of the gene mutated in the autosomal recessive disease hereditary hemochromatosis (Feder, J. N., Gnirke, A., Thomas, W., Tsuchihashi, Z., Ruddy, D. A., Basava, A., Dormishian, F., Domingo, R. J., Ellis, M. C., Fullan, A., Hinton, L. M., Jones, N. L., Kimmel, B. E., Kronmal, G. S., Lauer, P., Lee, V. K., Loeb, D. B., Mapa, F. A., McClelland, E., Meyer, N. C., Mintier, ...

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