Serotonin (5-hydroxytryptamine (5-HT)) is an important neurotransmitter that regulates multiple events in the central nervous system. Many of the 5-HT functions are mediated via G protein-coupled receptors that are coupled to multiple heterotrimeric G proteins, including Gs, Gi, and Gq subfamilies (Martin, G. R., Eglen, R. M., Hamblin, M. W., Hoyer, D., and Yocca, F. (1998) Trends Pharmacol. Sc...

Serotonin (5-hydroxytryptamine (5-HT)) is an important neurotransmitter that regulates multiple events in the central nervous system. Many of the 5-HT functions are mediated via G protein-coupled receptors that are coupled to multiple heterotrimeric G proteins, including G(s), G(i), and G(q) subfamilies (Martin, G. R., Eglen, R. M., Hamblin, M. W., Hoyer, D., and Yocca, F. (1998) Trends Pharmac...

Antihemophilic factor (AHF, factor VIII) is a macromolecule that can be dissociated into two subcomponents. One, of high molecular weight (MW), forms precipitates with heterologous antiserum against AHF and supports ristocetin-induced aggregation of platelets. The other, of lower MW, has procoagulant activity. The plasma of patients with classic hemophilia contains a form of AHF with properties...

Unmixing problems in many areas such as hyperspectral imaging and differential optical absorption spectroscopy (DOAS) often require finding sparse nonnegative linear combinations of dictionary elements that match observed data. We show how aspects of these problems, such as misalignment of DOAS references and uncertainty in hyperspectral endmembers, can be modeled by expanding the dictionary wi...

Gu, B. and M.V. Hoyer. 2005. Community structure and environmental conditions in Florida shallow lakes dominated by submerged aquatic vegetation. Lake and Reserv. Manage. 21(4):403-410. Florida inland waters are dominated by shallow lakes, many of which support the growth of submerged aquatic vegetation (SAV). We examined the species composition and selected environmental variables of SAV-domin...

In multi-party interactions humans use available communication modes in predictable ways. For example, the dialogue theories of Conversational Implicature (Grice 1975) and Giveness Theory (Gundel, Hedberg et al. 1993) have both been applied successfully in the analysis of multi-party, multimodal settings (Chai, Prasov et al. 2005). At times people use multiple modes of communication in compleme...