Objectives Actigraphy is widely used to estimate sleep-wake time, despite limited information regarding the comparability of different devices and algorithms. We compared estimates of sleep-wake times determined by two wrist actigraphs (GT3X+ versus Actiwatch Spectrum [AWS]) to in-home polysomnography (PSG), using two algorithms (Sadeh and Cole-Kripke) for the GT3X+ recordings. Subjects and m...

Purpose While the individual and social costs of alcoholism or alcohol use disorder are well established, few are aware that medical problems can arise during detoxification, some of which can be life-threatening. This study determines if sustained treatment for Alcohol Withdrawal Syndrome (AWS) might be based on the strategic choices and expectations of patients and health care providers alike...

Most prostate cancers (PCs) become resistant to combined androgen blockade therapy with surgical or medical castration and antiandrogens after several years. Some of these refractory PCs regress after discontinuation of antiandrogen administration [antiandrogen withdrawal syndrome (AWS)]. Although the molecular mechanisms of the AWS are not fully understood because of the lack of suitable exper...

BACKGROUND We previously reported increased current density through L-type voltage-gated Ca(2+) (CaV1) channels in inferior colliculus (IC) neurons during alcohol withdrawal. However, the molecular correlate of this increased CaV1 current is currently unknown. METHODS Rats received three daily doses of ethanol every 8 hours for 4 consecutive days; control rats received vehicle. The IC was dis...

PURPOSE The purpose of the present study was to evaluate and document the use and efficacy of intensive non-avoidance group treatment for Bulgarian adults who stutter (AWS), to specify that changes are adopted in different speech situations (in the stabilization phase), and to demonstrate that changes are maintained after intensive therapy. METHODS Participants were AWS (n=15, 12 males) with ...

AIMS The objective of this study was to collect preliminary data on the efficacy and safety of pregabalin in attenuating the severity of alcohol withdrawal symptoms during detoxification treatment in alcohol dependence. METHODS Forty-two alcohol-dependent patients with an alcohol withdrawal syndrome (AWS) were included in the prospective randomized double-blind placebo-controlled trial during...

provided the original work is properly cited. CC Klippel-Feil syndrome (KFS) is a congenital anomaly of the cervical vertebral segments presenting three characteristics: an extremely short neck, low hairline, and significantly restricted range of motion of the neck. KFS is one of the congenital causes of difficult airway management because of these characteristic features, and patients with KFS...

Corresponding author: Keon-Sik Kim, M.D., Department of Anesthesiology and Pain Medicine, Kyung Hee University Medical Center, Hoegidong, Dongdaemun-gu, Seoul 130-702, Korea. Tel: 82-2-958-8591, Fax: 82-2-958-8580, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/license...